DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17565 and AgaP_AGAP001729

DIOPT Version :9

Sequence 1:	NP_650540.1	Gene:	CG17565 / 41989	FlyBaseID:	FBgn0038424	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_321357.4	Gene:	AgaP_AGAP001729 / 1281446	VectorBaseID:	AGAP001729	Length:	458	Species:	Anopheles gambiae

Alignment Length:	425	Identity:	239/425 - (56%)
Similarity:	295/425 - (69%)	Gaps:	15/425 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RNFQRLKSYIFDDEKVSTTTSREQQKTESSVEKCFDRFEQIMFTDPRLTQIFRLEHQYYLDAMLR 74
            |...:.|.:..:||...|.:|.:|.|||:|:|:.:||:||:...|..|.::.|.:|..||...|.
Mosquito     8 RTLSQYKRFQTNDEGRKTFSSIDQIKTEASIERIYDRYEQLAALDATLPKLLRGDHARYLQLSLE 72

  Fly    75 RLPSNYECLDSSRAWCVYWILQAAQLLSFNFDDQTLNHVVQFLSNCRSPTGGFGGGPGQYAHLAP 139
            ||.:.||.|||||.|.|||||.||.:|:..|..:.|:.||.||..||...|||||||||..|||.
Mosquito    73 RLSTAYESLDSSRPWMVYWILNAASILNLRFPHELLDRVVDFLVKCRGKDGGFGGGPGQDPHLAT 137

  Fly   140 TYAAVNSLCIIGSEQAYRAIDRPTLVQFLFSVRDSDGSFRLHVDGETDVRGAYCAISCAKLLNLP 204
            ||||||||||||:::|..|||||:|.:|::|||:|:|:||:||.||.||||||||||.|||.:..
Mosquito   138 TYAAVNSLCIIGTDRALSAIDRPSLKRFMWSVRESNGAFRMHVGGEVDVRGAYCAISAAKLCSFT 202

  Fly   205 EPVIKELFAGTGDWIAQCQTYEGGFGGAPGLEAHGGYTFCGIAGLALLNEADKCDRQALLKWTLR 269
            ....:.||.||..|||:||||||||||||.|||||||:||..|.|.||...::||.:|||:||:.
Mosquito   203 PEDEQRLFEGTSGWIAECQTYEGGFGGAPDLEAHGGYSFCAAAALMLLGGENRCDLKALLRWTVN 267

  Fly   270 RQMTYEGGFQGRTNKLVDGCYSFWVGATIPITQ---ATLSGVDKQMEHTLFDVEALQEYILLCCQ 331
            |||.||||||||||||||||||||.||.:||.|   |...|....|..:||:..|||||:|:|||
Mosquito   268 RQMAYEGGFQGRTNKLVDGCYSFWQGALVPIVQGLIARAEGNQSIMNVSLFNRYALQEYVLICCQ 332

  Fly   332 KQSGGLIDKPGKPQDLYHTCYTLSGVSIAQHSECASSPQVLGDTINELLPTHPLFNIPPKSVAAA 396
            :.:||||||||||.|||||||||||:::|||.|..|.|.||||..||:|||||:.|||||:...|
Mosquito   333 RPNGGLIDKPGKPADLYHTCYTLSGLAVAQHCETHSPPLVLGDERNEVLPTHPVHNIPPKAALDA 397

  Fly   397 RSHF-------SNSNDTEFLGK-----DSPSKEES 419
            ..:|       |.|.:....||     |:.|:.||
Mosquito   398 YRYFLELDQPGSASEEKHCNGKSADPMDACSENES 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17565	NP_650540.1	PLN02710	27..403	CDD:215380	228/385 (59%)
CG17565	NP_650540.1	FTase	62..360	CDD:239223	189/300 (63%)
AgaP_AGAP001729	XP_321357.4	PLN02710	23..401	CDD:215380	226/377 (60%)
AgaP_AGAP001729	XP_321357.4	FTase	63..361	CDD:239223	188/297 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	87	1.000	Domainoid score	I14621
eggNOG	1	0.900	-	-		E1_COG5029
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1535
Inparanoid	1	1.050	475	1.000	Inparanoid score	I3263
OMA	1	1.010	-	-		QHG54572
OrthoDB	1	1.010	-	-		D1042804at2759
OrthoFinder	1	1.000	-	-		FOG0004877
OrthoInspector	1	1.000	-	-		oto110042
Panther	1	1.100	-	-	LDO	PTHR11774
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3440
TreeFam	1	0.960	-	-
	13	12.940