Protein Alignment Fntb and CHURC1-FNTB

DIOPT Version :10

• Sequence 1: NP_650540.1
• Gene: Fntb / 41989
• FlyBaseID: FBgn0038424
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001189488.1
• Gene: CHURC1-FNTB / 100529261
• HGNCID: 42960
• Length: 498
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 202/393 - (51%)
• Similarity: 250/393 - (63%)
• Gaps: 22/393 - (5%)

  Fly    33 QQKTESSVEKCFD--RFEQIMFTDPRLTQIFRLEHQYYLDAMLRRLPSNYECLDSSRAWCVYWIL 95
            |.|.|..:::.|.  :|..::   |||. :.|.:|.:||...||:|...|||||:||.|..||||
Human   109 QAKVEEKIQEVFSSYKFNHLV---PRLV-LQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWIL 169

  Fly    96 QAAQLLSFNFDDQTLNHVVQFLSNCRSPTGGFGGGPGQYAHLAPTYAAVNSLCIIGSEQAYRAID 160
            .:.:||...........|.|||..|:||.||||||||||.||||||||||:|||||:|:||..|:
Human   170 HSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIIN 234

  Fly   161 RPTLVQFLFSVRDSDGSFRLHVDGETDVRGAYCAISCAKLLNLPEPVIKELFAGTGDWIAQCQTY 225
            |..|:|:|:|::..||||.:||.||.|||.||||.|.|.|.|:..|   :||.||.:|||:||.:
Human   235 REKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITP---DLFEGTAEWIARCQNW 296

  Fly   226 EGGFGGAPGLEAHGGYTFCGIAGLALLNEADKCDRQALLKWTLRRQMTYEGGFQGRTNKLVDGCY 290
            |||.||.||:||||||||||:|.|.:|......:.::||:|...|||.:|||||||.||||||||
Human   297 EGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCY 361

  Fly   291 SFWVGATIPITQATLSGVDK---QMEHTLFDVEALQEYILLCCQKQSGGLIDKPGKPQDLYHTCY 352
            |||....:|:....|.....   .|.|.:|..:|||||||:|||..:|||:|||||.:|.|||||
Human   362 SFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCY 426

  Fly   353 TLSGVSIAQH--SECASSPQVLGDTINELLPTHPLFNIPPKSVAAARSHFSNSNDTEFLGKDSPS 415
            .|||:|||||  |.......|||...|.|.||||::||.|..|..|        .|.||.|..|.
Human   427 CLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQA--------TTYFLQKPVPG 483

  Fly   416 KEE 418
            .||
Human   484 FEE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fntb	NP_650540.1	FTase	62..360	CDD:239223	168/300 (56%)
CHURC1-FNTB	NP_001189488.1	Churchill	28..>109	CDD:461950	202/393 (51%)
		FTase	136..434	CDD:239223	168/300 (56%)