Protein Alignment ss and bmal1b

DIOPT Version :10

• Sequence 1: NP_001163629.2
• Gene: ss / 41988
• FlyBaseID: FBgn0003513
• Length: 1015
• Species: Drosophila melanogaster
• Sequence 2: XP_005166673.1
• Gene: bmal1b / 352935
• ZFINID: ZDB-GENE-030408-1
• Length: 676
• Species: Danio rerio
• Alignment Length: 598
• Identity: 124/598 - (20%)
• Similarity: 228/598 - (38%)
• Gaps: 163/598 - (27%)

  Fly    31 SNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDNGVL 95
            |...||.|:::|:.:|.||||:|....:..|||:|::||::|.:::|..            ....
Zfish   134 SQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLR------------GAAN 186

  Fly    96 PHIHAHDGYRTRELGAFEHGLLDGD----MFLQALNGFLMILTCE-GEVFFATHSIESYLGFHQS 155
            |:..|:          ::...|..|    :.|:|.:|||.::.|: |::.|.:.|:...|.:.|:
Zfish   187 PYTEAN----------YKPAFLSDDELKHLILKAADGFLFVVGCDRGKILFVSESVYKILNYSQN 241

  Fly   156 DIVHQSVYELVHSEDREELQRQLLWNSFLPAD-----MSSMQLAETLAPDKALY---LERSFTVR 212
            |::.||:::.:|.:|..:::.||..:...|.:     .:.:.:...:||..:..   ..|||..|
Zfish   242 DLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVRTDIAPSPSRLCSGARRSFFCR 306

  Fly   213 FRCL----------LDNTSGFLRLDIRGRIKVLHGQNRKTEEPPLALFAYCTPFG------PPS- 260
            .:|.          ..:|....:.| |.....:|........||       |..|      |.:
Zfish   307 MKCNRSMVKMEDKDFPSTCSKKKAD-RKSFCTIHSTGYLKSWPP-------TKMGLDEDNEPDNE 363

  Fly   261 ------LLEI----PH------------KENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMG 303
                  |:.|    ||            |...:.|:|.:|...|.:|||...||.|...||:...
Zfish   364 GCNLSCLVAIGRLHPHIVPQPVNGDIRVKPTEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTS 428

  Fly   304 GYDLVHYDDLAYVASAHQELLKTGAS-GMIAYRYQKKDGEWQWLQTSSRLVYKN---SKPDFVIC 364
            .|:..|.||:.::|..|:::|:.... ....|:::.|||.:..|: |....:.|   .:.::::.
Zfish   429 FYEYFHQDDIGHLAECHRQVLQMREKINTHCYKFKIKDGSFITLR-SRWFSFMNPWTKEVEYIVS 492

  Fly   365 THRQLMD------EEGHDLL--GKRTMDFKVSYLDTGLASTYFSEADQLVVPPSTSPTAHALPPP 421
            |:..:..      |.|...|  ..::||..::..|                  .:..|...||
Zfish   493 TNTVVSGSSVDGAEPGFPQLSASPQSMDSVLTAAD------------------GSGKTVPGLP-- 537

  Fly   422 VTPTRP-----NRRYKTQLRDF-------LSTCRSKRKLQQQNQPQTQQTSPLGGQVGSPAPAVA 474
             ..||.     .|....::.:.       .|:|.|.......:.|....:||...::.:..
Zfish   538 -GGTRAGAGKIGRMIAEEVMEIHRIRGSSPSSCGSSPLNISNSTPPPDTSSPAARKMSNGG---- 597

  Fly   475 VEYLPD-PAAAVAAAYSNLNPMYTTSPYASAADNLYMGSSMPANAFYPVSENLFHQYRLQGAVGG 538
               .|| |:|.:.:...::...|:.|...|  ||.::|.                         |
Zfish   598 ---TPDIPSAGLGSGQDSIGYPYSNSSILS--DNSHIGI-------------------------G 632

  Fly   539 YYTDYPHSGAPAS 551
            ...|.|.|.:|:|
Zfish   633 DIMDEPGSSSPSS 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ss	NP_001163629.2	bHLH-PAS_spineless_like	24..87	CDD:381573	19/55 (35%)
		PAS	123..178	CDD:214512	16/55 (29%)
		PAS_3	282..366	CDD:430001	23/87 (26%)
bmal1b	XP_005166673.1	bHLH-PAS_ARNTL_PASD3	123..186	CDD:381444	19/63 (30%)
		PAS	205..264	CDD:214512	16/58 (28%)
		PAS_11	395..498	CDD:464214	27/103 (26%)