Protein Alignment ss and clocka

DIOPT Version :10

• Sequence 1: NP_001163629.2
• Gene: ss / 41988
• FlyBaseID: FBgn0003513
• Length: 1015
• Species: Drosophila melanogaster
• Sequence 2: NP_571032.2
• Gene: clocka / 30140
• ZFINID: ZDB-GENE-990630-14
• Length: 892
• Species: Danio rerio
• Alignment Length: 987
• Identity: 212/987 - (21%)
• Similarity: 338/987 - (34%)
• Gaps: 263/987 - (26%)

  Fly    28 VTKSNPSKRHRERLNAELDLLASLLPFEQNILSKLDRLSILRLSVSYLRTKSYFQVVMHKDKEDN 92
            |:::...|:.|::.|..:..|.::||....   |:|:.:||:.|:.:||          |.||..
Zfish    28 VSRNRSEKKRRDQFNVLIKELGTMLPGNTR---KMDKSTILQKSIDFLR----------KHKEIA 79

  Fly    93 GVLPHIHAHDGYRTRELGAFEHGLLDGDMFLQALNGFLMILTCEGEVFFATHSIESYLGFHQSDI 157
            ...........::...|...|.    ..:.|:||:||.:.:..:|.:.:.:.|:.|.|....||:
Zfish    80 AQSESSEIRQDWKPPFLSNEEF----TQLMLEALDGFFLAIMTDGNIIYVSESVTSLLEHLPSDL 140

  Fly   158 VHQSVYELVHSEDREELQRQLLWNSFLPADMSSMQLAETLAPDKALYLERSFTVRFRCLLDNTSG 222
            |.|::...:...:..|:.:.|         .:.|...|||.||   ||:....:.|.|.:
Zfish   141 VDQNLLNFLPLGEHSEVYKAL---------STHMLEGETLTPD---YLKTKNQLEFCCHM----- 188

  Fly   223 FLRLDIRGRIKVLHGQNRKTEEPPL---------------------------------------A 248
                 :||.|        ..:|||:                                       .
Zfish   189 -----LRGTI--------DPKEPPVYEYVKFIGNFKSLNTVPNSTRNGFEGVIQRSLRHAFEDRV 240

  Fly   249 LFAYCTPFGPPSLL------EIPHKENMFKSKHKLDFSLVSMDQRGKHILGYADAELVNMGGYDL 307
            .|........|..:      |.|::|  |.|:|.|::..:.:|.|...|:||...|::...|||.
Zfish   241 CFIATVRLAKPQFIKEMCTVEEPNEE--FTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDY 303

  Fly   308 VHYDDLAYVASAHQELLKTGASGMIAYRYQKKDGEWQWLQTSSRLVYK--NSKPDFVICTH---- 366
            .|.|||..:|..|:.|::.|......||:..|..:|.||||...:.|.  ||:|:|::|||
Zfish   304 YHVDDLETLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVS 368

  Fly   367 ---------RQL-MDEEGHDLLGKRTMDF-KVSYLDTGLASTYFSEADQLVVPPSTS-----PTA 415
                     |:| ::|...::...::.|. ..|.|:|..........|....|.::|     .::
Zfish   369 YAEVRAEQRRELGIEESPPEISADKSQDSGSESQLNTSSLKEALERFDHSRTPSASSRSSRKSSS 433

  Fly   416 HAL--PPPVTPTRPNRRYKTQLRDFLSTCR--SKRKLQQQNQPQTQQTSPLGGQVGSPAPAVAVE 476
            |..  .|..|.|:......|..|..:|...  |:|:....:|..:.||:  |..:|:  ..|:..
Zfish   434 HTAVSDPTSTQTKLQTDRSTPPRQSVSAIEMTSQRRSSISSQSMSSQTT--GQTMGT--SLVSQP 494

  Fly   477 YLPDPAAAVAAAYSNLNPMYTTSPYASAADNL-----YMGSSMPANAFYPVSENLFHQYRLQGAV 536
            ..|....|      .:.|:...|....|..:|     .....:.||......|....|..||...
Zfish   495 QQPQTLQA------TVQPVLQFSTQMDAMQHLKEQLEQRTRMIEANIQRQQEELRQIQDELQRVQ 553

  Fly   537 G-GYYTDYPHSG----------APASAYVANGFLSYDGYAIASKADEKWQETGKYYSGYSSGYGS 590
            | |.......||          ..:|:....|.||..|..:.:...:     ....|.:||...:
Zfish   554 GQGLQMFLQPSGGGLNLSSVQLTQSSSVQTAGTLSMQGAVVPTATLQ-----SSLQSTHSSTQHT 613

  Fly   591 PTSTPQQIPLKTPK--------------------SSPQVMEVISCSSDGPSPVGGATPNGVGSVT 635
            .|..|||..::...                    .|||  ..:..|......:...|...|..::
Zfish   614 VTQHPQQTAVQQQNLLRDQTTNLNQQSQRSTHTLQSPQ--GALPASLYNTMMISQPTQANVVQIS 676

  Fly   636 PKVELAGTTAAAAAGQDPYERQ----------TVLMWGTTHSSG--VPLNSHGGRTGAGNPASPQ 688
            ..:....:|:.||......:||          |.|:.|......  ||.....|:....  .:||
Zfish   677 TSLAQNSSTSGAAVATFSQDRQIRFPATQQLLTKLVTGPMACGAVMVPTTMFMGQVVTA--FAPQ 739

  Fly   689 RSTPLGNGLG-YASANNNNNDLEPATAAKWNGTKELPGKSGSASTPESYQ------MQHDDSG-- 744
            :..|....:. ..||...:.........:...|.:..|::.:..|.:..|      :.|.:..
Zfish   740 QGQPQTISIAQQPSAQTADQQTHTQAQTQAAATAQQQGQNQAQLTQQQTQFLQAPRLLHSNQSTQ 804

  Fly   745 --------LYSASSHTTSPQQ-----QQQQQLQQSQRGVGSNVSAPSSSLTSTGTDQQAVHPSSC 796
                    |....:.||:.||     ||||||||.|:                           .
Zfish   805 LILQAAFPLQQQGTFTTATQQQQQLHQQQQQLQQQQQ---------------------------L 842

  Fly   797 HQQQQQQQQQHHHAHPHPHSHHHHHHHHHHETAHQHSSEIILTTHHQQQSQQQQQSLAGYPLHHQ 861
            .|||||||||....|                  .|...::      |||.|||||.||.   |..
Zfish   843 QQQQQQQQQQLQQQH------------------QQQQQQL------QQQHQQQQQQLAA---HRS 880

  Fly   862 LVGVGSGSPPPQ 873
            .......:||||
Zfish   881 DSMTERSNPPPQ 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ss	NP_001163629.2	bHLH-PAS_spineless_like	24..87	CDD:381573	14/58 (24%)
		PAS	123..178	CDD:214512	14/54 (26%)
		PAS_3	282..366	CDD:430001	31/85 (36%)
clocka	NP_571032.2	bHLH-PAS_CLOCK	20..80	CDD:381577	17/64 (27%)
		PAS	100..>169	CDD:395786	17/81 (21%)
		PAS_11	265..368	CDD:464214	38/104 (37%)
		SP1-4_N	<498..624	CDD:425404	27/136 (20%)