Protein Alignment Manf and Manf

DIOPT Version :10

• Sequence 1: NP_477445.1
• Gene: Manf / 41983
• FlyBaseID: FBgn0027095
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_001387993.1
• Gene: Manf / 315989
• RGDID: 1307252
• Length: 179
• Species: Rattus norvegicus
• Alignment Length: 166
• Identity: 84/166 - (50%)
• Similarity: 117/166 - (70%)
• Gaps: 7/166 - (4%)

  Fly     8 VVIGFLATLAQTSLALKEEDCEVCVKTVRRFADSLDDSTKKDY----KQIETAFKKFCKAQKNKE 68
            :.:....::...|.||:..|||||:..:.||...|.|   :|.    ..||....|||:..:.||
  Rat     7 LAVALALSVLPDSRALRPGDCEVCISYLGRFYQDLKD---RDVTFSPATIEEELIKFCREARGKE 68

  Fly    69 HRFCYYLGGLEESATGILNELSKPLSWSMPAEKICEKLKKKDAQICDLRYEKQIDLNSVDLKKLK 133
            :|.|||:|..:::||.|:||:||||:..:|.|||||||||||:|||:|:|:|||||::||||||:
  Rat    69 NRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLR 133

  Fly   134 VRDLKKILNDWDESCDGCLEKGDFIKRIEELKPKYS 169
            |::|||||:||.|.|.||.||.|:|::|.||.|||:
  Rat   134 VKELKKILDDWGEMCKGCAEKSDYIRKINELMPKYA 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Manf	NP_477445.1	ARMET_N	27..122	CDD:466306	49/98 (50%)
		ARMET_C	126..168	CDD:462997	26/41 (63%)
Manf	NP_001387993.1	ARMET_N	26..122	CDD:466306	50/99 (51%)
		Interacts with ERN1, EIF2AK3 and ATF6. /evidence=ECO:0000250|UniProtKB:P55145	93..155		42/61 (69%)
		Interacts with HSPA5. /evidence=ECO:0000250|UniProtKB:Q9CXI5	126..169		28/43 (65%)
		ARMET_C	126..168	CDD:462997	27/41 (66%)