DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pad and klf13

DIOPT Version :9

Sequence 1:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_001070240.1	Gene:	klf13 / 767805	ZFINID:	ZDB-GENE-060929-1274	Length:	258	Species:	Danio rerio

Alignment Length:	311	Identity:	74/311 - (23%)
Similarity:	117/311 - (37%)	Gaps:	90/311 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   539 QTKPQPQVKQQQTAGLSASGAPTATSANQAAMQRLSSNTTITKVPKQPASLPAPAPTSNPAKLPM 603
            :|||       :||....:|        :.|.:.|..|:::..|.:..|......|.|
Zfish    26 ETKP-------ETAAAQRNG--------EEAKEPLKDNSSLFVVARILADFNQQTPAS------- 68

  Fly   604 LNKQNITISRISMQTAPKAQSKPSTTSPT--PASQPIPVSVPALSQAQPPPLAAQHKKIVRKPPE 666
                      .:.|...|.:|.|.|.:|:  ..:...|.::|..|..:      |..|..|...|
Zfish    69 ----------FAEQAKIKEESTPPTATPSGDDGNSATPTAIPGDSALK------QRGKRFRGRVE 117

  Fly   667 NQDTSGQKVKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLICPTCKREFKKKEHLTQHVKLHA 731
            :.                  :||:: ....:||             |::.:.|..||..|::.|.
Zfish   118 HD------------------APQKK-HKCHYSG-------------CEKVYGKSSHLKAHLRTHT 150

  Fly   732 GLRPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIHTQTSTETL 796
            |.|||.|:...|.|.|:|.:.|:||..:|:|:|.:.|.:|.|.|.|.|:|.||.|.|:......|
Zfish   151 GERPFPCTWPDCSKKFARSDELARHYRTHTGEKKFGCPLCDKRFMRSDHLMKHARRHSDFQPAML 215

  Fly   797 YCCDVCNKNFATKLHYEKHREMHKKIRP-------ESAAPGATASPAAAPA 840
                       .:.|...:..:...:||       .|.|...|.|||.:||
Zfish   216 -----------KRQHGGGNAAVSSSMRPGSLSDYSRSDASSPTLSPALSPA 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	5/19 (26%)
		zf-C2H2	736..760	CDD:278523	9/23 (39%)
		C2H2 Zn finger	738..760	CDD:275368	8/21 (38%)
		zf-H2C2_2	752..777	CDD:290200	10/24 (42%)
		zf-C2H2	766..788	CDD:278523	10/21 (48%)
		C2H2 Zn finger	768..788	CDD:275368	10/19 (53%)
		zf-H2C2_2	780..808	CDD:290200	6/27 (22%)
		C2H2 Zn finger	799..819	CDD:275368	1/19 (5%)
klf13	NP_001070240.1	zf-C2H2_8	127..209	CDD:292531	34/94 (36%)
		C2H2 Zn finger	127..149	CDD:275368	7/34 (21%)
		zf-H2C2_2	141..168	CDD:290200	12/26 (46%)
		C2H2 Zn finger	157..179	CDD:275368	8/21 (38%)
		zf-H2C2_2	171..194	CDD:290200	9/22 (41%)
		C2H2 Zn finger	187..207	CDD:275368	10/19 (53%)
		zf-C2H2	187..207	CDD:278523	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910