DRSC/TRiP Functional Genomics Resources

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Protein Alignment pad and ZNF69

DIOPT Version :9

Sequence 1:NP_650534.2 Gene:pad / 41981 FlyBaseID:FBgn0038418 Length:924 Species:Drosophila melanogaster
Sequence 2:XP_006722936.1 Gene:ZNF69 / 7620 HGNCID:13138 Length:569 Species:Homo sapiens


Alignment Length:197 Identity:55/197 - (27%)
Similarity:85/197 - (43%) Gaps:20/197 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   671 SGQK-VKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLICPTCKREFKKKEHLTQHVKLHAGLR 734
            ||:| .|..:..:..:.|.........|:| |.|..    |..|.:.|:...||..|.:.|.|.:
Human   386 SGEKPYKCKQCGKAFIHSSSLRYHERIHTG-EKPYE----CKQCGKAFRSSSHLQLHGRTHTGEK 445

  Fly   735 PFKCSEEGCDKTFSRKEHL------SRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIHTQTST 793
            |::|.|  |.|.|...::|      ..|:..|||::.|.|::|.|.|....:|.:|.:.||   .
Human   446 PYECQE--CGKAFRSMKNLQSHERTQTHVRIHSGERPYKCKLCGKGFYCPKSLQRHEKTHT---G 505

  Fly   794 ETLYCCDVCNKNFATKLHYEKHREMHKKIRPESAAPGATASPAAAPALTHVRSNGQVPNKAVFEI 858
            |.||.|..|.:.|::...:..|...|...:|........|..||:....|.|::   |....:|.
Human   506 EKLYECKQCGEAFSSSSSFRYHERTHTGEKPYKCKQCGKAFRAASVLRMHGRTH---PEDKPYEC 567

  Fly   859 KQ 860
            ||
Human   568 KQ 569

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
padNP_650534.2 zf-AD 16..87 CDD:214871
C2H2 Zn finger 710..730 CDD:275368 6/19 (32%)
zf-C2H2 736..760 CDD:278523 7/29 (24%)
C2H2 Zn finger 738..760 CDD:275368 7/27 (26%)
zf-H2C2_2 752..777 CDD:290200 10/30 (33%)
zf-C2H2 766..788 CDD:278523 7/21 (33%)
C2H2 Zn finger 768..788 CDD:275368 6/19 (32%)
zf-H2C2_2 780..808 CDD:290200 10/27 (37%)
C2H2 Zn finger 799..819 CDD:275368 4/19 (21%)
ZNF69XP_006722936.1 KRAB 27..>67 CDD:214630
KRAB 27..66 CDD:279668
C2H2 Zn finger 169..189 CDD:275368
C2H2 Zn finger 197..217 CDD:275368
COG5048 222..>540 CDD:227381 46/163 (28%)
C2H2 Zn finger 225..245 CDD:275368
zf-H2C2_2 241..262 CDD:290200
C2H2 Zn finger 253..273 CDD:275368
zf-H2C2_2 266..290 CDD:290200
C2H2 Zn finger 281..301 CDD:275368
zf-H2C2_2 295..318 CDD:290200
C2H2 Zn finger 309..329 CDD:275368
C2H2 Zn finger 337..357 CDD:275368
zf-H2C2_2 349..372 CDD:290200
C2H2 Zn finger 365..385 CDD:275368
zf-H2C2_2 377..400 CDD:290200 4/13 (31%)
C2H2 Zn finger 393..413 CDD:275368 1/19 (5%)
zf-H2C2_2 405..430 CDD:290200 7/29 (24%)
C2H2 Zn finger 421..441 CDD:275368 6/19 (32%)
C2H2 Zn finger 449..468 CDD:275368 6/20 (30%)
C2H2 Zn finger 483..503 CDD:275368 6/19 (32%)
zf-H2C2_2 495..520 CDD:290200 10/27 (37%)
C2H2 Zn finger 511..531 CDD:275368 4/19 (21%)
zf-H2C2_2 523..546 CDD:290200 3/22 (14%)
C2H2 Zn finger 539..559 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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