DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pad and zic2b

DIOPT Version :9

Sequence 1:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_001001820.1	Gene:	zic2b / 570746	ZFINID:	ZDB-GENE-030219-92	Length:	427	Species:	Danio rerio

Alignment Length:	153	Identity:	52/153 - (33%)
Similarity:	77/153 - (50%)	Gaps:	18/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   696 THSGSE---APTTSGLIC--PTCKRE---FKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKEH 752
            ||..:|   .|.....||  ..|.||   ||.|..|..|:::|.|.:||.|...||.|.|:|.|:
Zfish   237 THVSTEHVGGPEQCNHICFWEECPRESKPFKAKYKLVNHIRVHTGEKPFACPFPGCGKVFARSEN 301

  Fly   753 LSRHLVSHSGQKMYTCEV--CKKPFSRKDNLNKHRRIHTQTSTETLYCCDVCNKNFATKLHYEKH 815
            |..|..:|:|:|.:.||.  |.:.|:...:..||..:||   ::..|.|.:|:|::.......||
Zfish   302 LKIHKRTHTGEKPFLCEFEGCDRRFANSSDRKKHMHVHT---SDKPYLCKLCDKSYTHPSSLRKH 363

  Fly   816 REMHKKIRPESAAPGATASPAAA 838
            .::|     |..||.|.:|||.:
Zfish   364 MKVH-----EDQAPIADSSPAGS 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	9/24 (38%)
		zf-C2H2	736..760	CDD:278523	10/23 (43%)
		C2H2 Zn finger	738..760	CDD:275368	9/21 (43%)
		zf-H2C2_2	752..777	CDD:290200	9/26 (35%)
		zf-C2H2	766..788	CDD:278523	6/23 (26%)
		C2H2 Zn finger	768..788	CDD:275368	6/21 (29%)
		zf-H2C2_2	780..808	CDD:290200	8/27 (30%)
		C2H2 Zn finger	799..819	CDD:275368	5/19 (26%)
zic2b	NP_001001820.1	C2H2 Zn finger	259..279	CDD:275368	8/19 (42%)
		zf-H2C2_2	272..298	CDD:290200	11/25 (44%)
		C2H2 Zn finger	290..309	CDD:275368	8/18 (44%)
		zf-H2C2_2	301..328	CDD:290200	9/26 (35%)
		C2H2 Zn finger	317..339	CDD:275368	6/21 (29%)
		zf-C2H2	345..367	CDD:278523	6/21 (29%)
		C2H2 Zn finger	347..367	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000