Protein Alignment pad and Sp3

DIOPT Version :10

• Sequence 1: NP_650534.2
• Gene: pad / 41981
• FlyBaseID: FBgn0038418
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001414334.1
• Gene: Sp3 / 367846
• RGDID: 1583765
• Length: 781
• Species: Rattus norvegicus
• Alignment Length: 767
• Identity: 182/767 - (23%)
• Similarity: 282/767 - (36%)
• Gaps: 193/767 - (25%)

  Fly   144 MQPQQQYTITMDNG---------VQQQQQQHQAMPEVQIKSERQTALEEFIRLKPDIKITPL--- 196
            ::.::...:.:|:|         :||||||.|........:..|           |.:.:||
  Rat     8 VKQEEMAALDVDSGGGGGGHGEYLQQQQQQQQHGNGAAAAAAAQ-----------DTQPSPLALL 61

  Fly   197 ----GKKEPISPAKPQQQ---------------------------HSLQSQTVTPTINPTQLQLQ 230
                .|..|.||...:::                           :..:..:.|||      .::
  Rat    62 AATCSKIGPPSPGDDEEEAAAAAGVPAAAAGATGDLASAQLGGAPNRWEVLSATPT------TIK 120

  Fly   231 PQLGDQLQPLWQQIQQLQLQQQLQQLTNQLQATTQYSVAQDDTSSSGDSKKPKLNFV--LSSPTA 293
            .:.|:.:|.........|....||.|.||    ..:|||....||:|.....:...:  :.|..|
  Rat   121 DEAGNLVQIPGAATSSGQYVLPLQNLQNQ----QIFSVAPGSDSSNGTVSNVQYQVIPQIQSTDA 181

  Fly   294 PQ----FTTSMPQFGGSQPQIQLQLMPGSG-GVTSAGTVPA----------QTQLNAAAL-LSSL 342
            .|    ||.|....|.:|...|:|::|||. .:.::||.||          |.|:...|: .||.
  Rat   182 QQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSF 246

  Fly   343 AG-PQSTTNL---LSPNKCFLPITIRD------ENSDQQIVAHIDTKNLVLPT---------TYQ 388
            .| .|...|:   |..|..|:||...|      ..|.|.:.|.|:....::.|         :.:
  Rat   247 PGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSER 311

  Fly   389 VQMKLQPQLATADGQPIMQLTPTSIPATLQLTPQTLGNPGSAFQGT---TVTQ----------NQ 440
            ...::.|.:...:....: ..|||..:.|   |.|:.:.|...|.|   |.|.          |.
  Rat   312 TGERVSPDVNETNADTDL-FVPTSSSSQL---PVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNY 372

  Fly   441 FLAPQQPLTQLPNTAQVTSQQIIRSPHTSTTNSQLVIRNVTNIPPTPTTPTSSKKAPTFKTPSPK 505
            ..:|....||..|....|:|.:::  |....:||              .|||..:.....||
  Rat   373 IQSPVSEETQAQNIQVSTAQPVVQ--HLQLQDSQ--------------QPTSQAQIVQGITP--- 418

  Fly   506 QKPMPSPKSKTTVGPSSGGSNGTSTNEFKRLITQTKPQPQVKQQQTAGLSASGAPTATSANQAAM 570
                     :|..|..:.|.| .|....:.|..|..|...:.|.||  ::.||..|..:.....:
  Rat   419 ---------QTIHGVQASGQN-ISQQALQNLQLQLNPGTFLIQAQT--VTPSGQITWQTFQVQGV 471

  Fly   571 QRLSS----NTT---ITKVPKQPASL----PAPAPTSNPAKL---PMLNKQNITISRISMQTAPK 621
            |.|.:    ||.   ||..|.|..:|    ...|.||.|..|   .:.|.|.:|::.|.   :..
  Rat   472 QNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSID---STG 533

  Fly   622 AQSKPSTTSPTPASQPIPVSVPALSQAQPPPLAAQ-------------HKKIVRKPPENQDTSGQ 673
            .|..|...:.:||...|       .:.:|.|...|             |.: |:...|..|...|
  Rat   534 IQLHPGENADSPADIRI-------KEEEPDPEEWQLSGDSTLNTNDLTHLR-VQVVDEEGDQQHQ 590

  Fly   674 KVKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLIC--PTCKREFKKKEHLTQHVKLHAGLRPF 736
            :.|..|......|:.::.|...|:.|.:...    ||  |.|.:.:.|..||..|::.|:|.|||
  Rat   591 EGKRLRRVACTCPNCKEGGGRGTNLGKKKQH----ICHIPGCGKVYGKTSHLRAHLRWHSGERPF 651

  Fly   737 KCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIH 788
            .|:...|.|.|:|.:.|.||..:|:|:|.:.|..|.|.|.|.|:|.||.:.|
  Rat   652 ICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTH 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..88	CDD:462262
		PHA03247	<497..709	CDD:223021	53/238 (22%)
		C2H2 Zn finger	710..730	CDD:275368	7/21 (33%)
		zf-C2H2	736..760	CDD:395048	9/23 (39%)
		C2H2 Zn finger	738..760	CDD:275368	8/21 (38%)
		zf-C2H2	766..788	CDD:395048	9/21 (43%)
		C2H2 Zn finger	768..788	CDD:275368	9/19 (47%)
		zf-C2H2	797..819	CDD:395048
		C2H2 Zn finger	799..819	CDD:275368
Sp3	NP_001414334.1	None