DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pad and odd

DIOPT Version :9

Sequence 1:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	70/336 - (20%)
Similarity:	119/336 - (35%)	Gaps:	74/336 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   586 PASLPAPAPTSNPAKL--PMLNKQNITISR------------------------ISMQTAPKAQS 624
            |...|...||..|.:.  |.::::.:....                        :.||...:...
  Fly    44 PMLTPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQ 108

  Fly   625 KPS--TTSPTPASQPIPVSVPALSQAQPPPLAAQHKKIVRKPPENQDTSGQKVKAARPPQQILPS 687
            .|.  ...||.::.|:.|....::.........|.::..::.|.:....|........|..:.|.
  Fly   109 APQQYPVYPTASADPVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHHHHHGHPHHPHPHPHHVRPY 173

  Fly   688 PQQEGQNATH------------------SGSEAPTTSG----------LICPTCKREFKKKEHLT 724
            |  .|.::.|                  :|..:...||          .||..|.|:|.|..:|.
  Fly   174 P--AGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQFICKYCNRQFTKSYNLL 236

  Fly   725 QHVKLHAGLRPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIHT 789
            .|.:.|...||:.|  :.|.|.|.|::||..|...||..|.:.|..|.|.|.:...|..|:..|.
  Fly   237 IHERTHTDERPYSC--DICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHL 299

  Fly   790 QTSTETLYCCDVCNKNFATKLHYEKHREMHKKIRPESAAPGATASPAAAPALTHVRSNGQVPNKA 854
            :   |..:.|.:|.::|..:.:.:.|.:.|.:...:...  .|.|||         ::..|||:|
  Fly   300 E---EGPHKCPICQRSFNQRANLKSHLQSHSEQSTKEVV--VTTSPA---------TSHSVPNQA 350

  Fly   855 VFEIKQERSAQ 865
            :...:.|..||
  Fly   351 LSSPQPENLAQ 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	7/19 (37%)
		zf-C2H2	736..760	CDD:278523	8/23 (35%)
		C2H2 Zn finger	738..760	CDD:275368	8/21 (38%)
		zf-H2C2_2	752..777	CDD:290200	10/24 (42%)
		zf-C2H2	766..788	CDD:278523	6/21 (29%)
		C2H2 Zn finger	768..788	CDD:275368	6/19 (32%)
		zf-H2C2_2	780..808	CDD:290200	7/27 (26%)
		C2H2 Zn finger	799..819	CDD:275368	4/19 (21%)
odd	NP_722922.1	COG5048	<203..334	CDD:227381	37/135 (27%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		zf-H2C2_2	234..259	CDD:290200	9/26 (35%)
		C2H2 Zn finger	250..270	CDD:275368	8/21 (38%)
		zf-H2C2_2	262..285	CDD:290200	9/22 (41%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-C2H2	304..326	CDD:278523	4/21 (19%)
		C2H2 Zn finger	306..326	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I2683
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050