DRSC/TRiP Functional Genomics Resources

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Protein Alignment pad and Zfp438

DIOPT Version :9

Sequence 1:NP_650534.2 Gene:pad / 41981 FlyBaseID:FBgn0038418 Length:924 Species:Drosophila melanogaster
Sequence 2:NP_001347376.1 Gene:Zfp438 / 240186 MGIID:2444919 Length:798 Species:Mus musculus


Alignment Length:608 Identity:137/608 - (22%)
Similarity:207/608 - (34%) Gaps:220/608 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   392 KLQPQLATADGQPIMQLTPTSI--PATLQLTPQTLGNPGSAFQGTTVTQNQFL---APQQ---PL 448
            |:.|::.|:...|    .|:||  ..:|.|.|:.||.|         |||..|   |.|:   .|
Mouse    40 KVVPKVLTSRVLP----CPSSISDQGSLTLMPKPLGMP---------TQNYALMQVAGQEGTFSL 91

  Fly   449 TQLPNTAQVTSQQIIRSPHTST-TNSQLVI--------------------RNVTNIPPTPTT--- 489
            ...||   |.|.|.::.|..|| .|.:|.|                    ::.::.||.|:.   
Mouse    92 VAFPN---VASAQPVQKPRMSTHENLKLPIPRYQPLSSQGLRKKQDLSSPKSGSSDPPGPSQLCH 153

  Fly   490 PTSSKKAPTFKTPSPKQKPM---------PSPKSKTTVGPSSGGSNG----TSTNEFKRLITQTK 541
            .|||.:|    .|.|..||.         |||.:..|...:||...|    ..||....|.....
Mouse   154 LTSSPQA----YPDPHHKPSLWKQMPTLNPSPTNINTATLTSGVGQGDLSPLVTNSCGDLELSAM 214

  Fly   542 P----QPQVKQQ------QTAGLSASGAPTATS-ANQAAMQRLSSNTTI--------TKVPKQPA 587
            |    :....||      |.||.:...|||..: |::...::|:|..|:        :.|||  .
Mouse   215 PVYTTEDSSSQQSLPASMQKAGCARKEAPTTPAIASEELKEQLASAQTVLSSAVQLLSVVPK--G 277

  Fly   588 SLP-APAP---TSNPAKLPMLNKQNITIS----------RISM--------QTAPKAQSKPSTTS 630
            .|| .|.|   |:...|:.. :..|..:|          |:|:        :.|.|..:...:..
Mouse   278 KLPILPLPRVKTTEVGKVES-DADNAELSLSGCRANCDERLSITEGFDAATEIASKIAALHGSKQ 341

  Fly   631 PTPASQPIPVSVPALSQAQPPP----------------LAAQHKK-----------IVRKPPENQ 668
            ....|...||:...||....|.                ||.|.|:           |.|.....|
Mouse   342 SACESAFCPVTKLDLSHKAKPSSGIKRRGRKWKVPDEILALQGKRRKCIIGMCGDGIERARNSPQ 406

  Fly   669 DTSGQKVK-AARPPQQILP---------------------SPQQEGQN------------ATHSG 699
            :...||.: |:|..:.|:|                     :|...||:            :..|.
Mouse   407 EARDQKPRVASRKYRNIMPKPVLVLSALAPLASHTAVLSQAPSSLGQDVLNNALPSKCLGSKQSD 471

  Fly   700 SEAPTTSGLI-------------CPTCKREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKE 751
            |..|..|.::             ||.|...|:.|.||..|:..|...||                
Mouse   472 SSTPKPSSVLRNGFSGIKKPWHMCPVCNYHFQFKHHLLDHMNTHTNRRP---------------- 520

  Fly   752 HLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRI-HTQTSTETLYCCDVCNKNFA-TKLHYEK 814
                          |:|.:|:|.:.|..:|:.|.:: |.....:.|.||:.|.|.|. .::::..
Mouse   521 --------------YSCGICRKTYVRPGSLSAHMKLHHGDNHPKKLVCCEFCAKVFGHVRVYFGH 571

  Fly   815 HREMHKKI-----RPESAAPGAT 832
            .:|:|:.:     .|....||.|
Mouse   572 LKEVHRVVISTEPSPSELQPGDT 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
padNP_650534.2 zf-AD 16..87 CDD:214871
C2H2 Zn finger 710..730 CDD:275368 8/19 (42%)
zf-C2H2 736..760 CDD:278523 0/23 (0%)
C2H2 Zn finger 738..760 CDD:275368 0/21 (0%)
zf-H2C2_2 752..777 CDD:290200 4/24 (17%)
zf-C2H2 766..788 CDD:278523 7/22 (32%)
C2H2 Zn finger 768..788 CDD:275368 6/20 (30%)
zf-H2C2_2 780..808 CDD:290200 9/29 (31%)
C2H2 Zn finger 799..819 CDD:275368 5/20 (25%)
Zfp438NP_001347376.1 C2H2 Zn finger 495..515 CDD:275368 8/19 (42%)
zf-H2C2_2 507..532 CDD:372612 10/54 (19%)
zf-C2H2 521..543 CDD:333835 7/21 (33%)
C2H2 Zn finger 523..543 CDD:275368 6/19 (32%)
C2H2 Zn finger 554..573 CDD:275368 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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