DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pad and Klf6

DIOPT Version :9

Sequence 1:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_035933.2	Gene:	Klf6 / 23849	MGIID:	1346318	Length:	318	Species:	Mus musculus

Alignment Length:	221	Identity:	54/221 - (24%)
Similarity:	93/221 - (42%)	Gaps:	47/221 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   595 TSNPAKLPMLNKQ---NITISRISMQTAPKAQSKPSTTSPTP--ASQPIP---VSVPALSQAQPP 651
            :|:|.:..:::..   |:..:.::...:.::.......|||.  .|.||.   |:...||.:
Mouse   117 SSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPIGEVLVNSGNLSSS--- 178

  Fly   652 PLAAQHKKIVRKPPENQDTSGQKVKAARPPQQI-------LPSPQQEGQNATHSGSEAPTTSGLI 709
                    ::..||.:.:.:       |...|:       ||||.:.....  ||......:|..
Mouse   179 --------VISTPPSSPEVN-------RESSQLWGCGPGDLPSPGKVRSGT--SGKSGDKGNGDA 226

  Fly   710 CPT------------CKREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKEHLSRHLVSHSG 762
            .|.            |::.:.|..||..|.:.|.|.:|::||.|||:..|:|.:.|:||...|:|
Mouse   227 SPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTG 291

  Fly   763 QKMYTCEVCKKPFSRKDNLNKHRRIH 788
            .|.:.|..|.:.|||.|:|..|.:.|
Mouse   292 AKPFKCSHCDRCFSRSDHLALHMKRH 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	6/31 (19%)
		zf-C2H2	736..760	CDD:278523	10/23 (43%)
		C2H2 Zn finger	738..760	CDD:275368	10/21 (48%)
		zf-H2C2_2	752..777	CDD:290200	9/24 (38%)
		zf-C2H2	766..788	CDD:278523	8/21 (38%)
		C2H2 Zn finger	768..788	CDD:275368	8/19 (42%)
		zf-H2C2_2	780..808	CDD:290200	3/9 (33%)
		C2H2 Zn finger	799..819	CDD:275368
Klf6	NP_035933.2	COG5048	212..>300	CDD:227381	26/89 (29%)
		zf-C2H2	235..259	CDD:278523	5/23 (22%)
		C2H2 Zn finger	240..259	CDD:275368	5/18 (28%)
		zf-H2C2_2	251..>267	CDD:290200	6/15 (40%)
		C2H2 Zn finger	267..289	CDD:275368	10/21 (48%)
		zf-H2C2_2	281..306	CDD:290200	9/24 (38%)
		C2H2 Zn finger	297..317	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910