DRSC/TRiP Functional Genomics Resources

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Protein Alignment pad and EGR3

DIOPT Version :9

Sequence 1:NP_650534.2 Gene:pad / 41981 FlyBaseID:FBgn0038418 Length:924 Species:Drosophila melanogaster
Sequence 2:XP_005273482.1 Gene:EGR3 / 1960 HGNCID:3240 Length:442 Species:Homo sapiens


Alignment Length:369 Identity:95/369 - (25%)
Similarity:138/369 - (37%) Gaps:84/369 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   506 QKPMPSPKSKTTVGPSSGGSNGTSTNEFKRLITQTKPQPQVKQQQTAGLSASGAPTATSANQAAM 570
            :||.|......:..|:.|....|...:|.........|..:....:||:  .|.|.|:.|     
Human   117 EKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGI--LGVPPASGA----- 174

  Fly   571 QRLSSNTTITKVPKQP-----ASLPAPAPTSNPAKL---------PMLNKQNITISRISMQTAPK 621
              ||:.|:...:.:.|     |..||..|.||...|         |..| ..:..|....|:|..
Human   175 --LSTQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGN-PGLAYSPQDYQSAKP 236

  Fly   622 AQSK--------------PSTTSPTPASQPI----PVSVPALSQAQPPPLAAQHKKIVRKPPENQ 668
            |...              |:.....|..:|.    |:.|      .|||:.         |.|. 
Human   237 ALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRV------NPPPIT---------PLET- 285

  Fly   669 DTSGQKVKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLICPTCKREFKKKEHLTQHVKLHAGL 733
             ....|.|...|....||.|              |.|   :.|...|::..:...|   .||.  
Human   286 -IKAFKDKQIHPGFGSLPQP--------------PLT---LKPIRPRKYPNRPSKT---PLHE-- 327

  Fly   734 RPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIHTQTSTETLYC 798
            ||..|..||||:.|||.:.|:|||..|:|.|.:.|.:|.:.|||.|:|..|.|.||   .|..:.
Human   328 RPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHT---GEKPFA 389

  Fly   799 CDVCNKNFATKLHYEKHREMHKKIRPESAAPGATASPAAAPALT 842
            |:.|.:.||.....::|.::|.|.:.:.|..|...|.::||.::
Human   390 CEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVS 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
padNP_650534.2 zf-AD 16..87 CDD:214871
C2H2 Zn finger 710..730 CDD:275368 3/19 (16%)
zf-C2H2 736..760 CDD:278523 12/23 (52%)
C2H2 Zn finger 738..760 CDD:275368 12/21 (57%)
zf-H2C2_2 752..777 CDD:290200 10/24 (42%)
zf-C2H2 766..788 CDD:278523 9/21 (43%)
C2H2 Zn finger 768..788 CDD:275368 9/19 (47%)
zf-H2C2_2 780..808 CDD:290200 9/27 (33%)
C2H2 Zn finger 799..819 CDD:275368 5/19 (26%)
EGR3XP_005273482.1 DUF3446 142..202 CDD:288757 15/68 (22%)
COG5048 324..>388 CDD:227381 31/68 (46%)
zf-C2H2 330..354 CDD:278523 12/23 (52%)
C2H2 Zn finger 332..354 CDD:275368 12/21 (57%)
zf-H2C2_2 346..371 CDD:290200 10/24 (42%)
COG5048 358..>431 CDD:227381 24/75 (32%)
C2H2 Zn finger 362..382 CDD:275368 9/19 (47%)
zf-H2C2_2 374..399 CDD:290200 9/27 (33%)
C2H2 Zn finger 390..410 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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