DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pad and Egr1

DIOPT Version :9

Sequence 1:NP_650534.2 Gene:pad / 41981 FlyBaseID:FBgn0038418 Length:924 Species:Drosophila melanogaster
Sequence 2:NP_031939.1 Gene:Egr1 / 13653 MGIID:95295 Length:533 Species:Mus musculus


Alignment Length:530 Identity:128/530 - (24%)
Similarity:191/530 - (36%) Gaps:141/530 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   466 PHTSTTNSQLVIRNVTNIPPTPTTPTSSKKAPTF--KTPSPKQKPMPSPKSKTTVGPSSGGSNGT 528
            ||:.|         :.|.|........|..||.|  ...:|:.....|..|.::.|...||||..
Mouse    24 PHSPT---------MDNYPKLEEMMLLSNGAPQFLGAAGTPEGSGGNSSSSTSSGGGGGGGSNSG 79

  Fly   529 STNEFKRLITQTKPQPQVKQQQTAGLSASGAPTATSANQAAMQRLSSNTTITKVPKQPASLP--- 590
            |        :...||.:..:|....|:..........|:.||..       |..|.|...||   
Mouse    80 S--------SAFNPQGEPSEQPYEHLTTESFSDIALNNEKAMVE-------TSYPSQTTRLPPIT 129

  Fly   591 -------APAPTSN----PAKLPMLNKQNITISRISMQTAPKAQSKPSTTSPTPASQPIPVSVPA 644
                   .|||.|.    |.  |:.:..:..:|..:..|:..:...|:.:|.:.|||..|:|...
Mouse   130 YTGRFSLEPAPNSGNTLWPE--PLFSLVSGLVSMTNPPTSSSSAPSPAASSSSSASQSPPLSCAV 192

  Fly   645 LSQAQPP-----PLAAQHKKIVRKPPENQDTSGQKVKAARPPQQILPS---------------PQ 689
            .|....|     |........:...|::|...|....|.:.|....|:               ||
Mouse   193 PSNDSSPIYSAAPTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAYPATKGGFQVPMIPDYLFPQ 257

  Fly   690 QEG---------------QN----------------ATHSGSE----APTT--SGLICPTCKREF 717
            |:|               :|                ||.|||:    ..||  |.||.|:..|::
Mouse   258 QQGDLSLGTPDQKPFQGLENRTQQPSLTPLSTIKAFATQSGSQDLKALNTTYQSQLIKPSRMRKY 322

  Fly   718 KKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLN 782
            ..:...|...:     ||:.|..|.||:.|||.:.|:||:..|:|||.:.|.:|.:.|||.|:|.
Mouse   323 PNRPSKTPPHE-----RPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLT 382

  Fly   783 KHRRIHTQTSTETLYCCDVCNKNFATKLHYEKHREMHKKIRPESAAPGATASPAAAPALTHVRSN 847
            .|.|.||   .|..:.||:|.:.||.....::|.::|.:.:.:.|.....|||||:       |.
Mouse   383 THIRTHT---GEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKSVVASPAAS-------SL 437

  Fly   848 GQVPNKAVFEIKQERSAQQTQTQQPPAQVMHVVTTQDLAGNTITITQAPDS-NMPGSLANYVQLG 911
            ...|:.                         |.|:......|...:..|.| :.||| :.|....
Mouse   438 SSYPSP-------------------------VATSYPSPATTSFPSPVPTSYSSPGS-STYPSPA 476

  Fly   912 FSQFQNPSAS 921
            .|.|.:||.:
Mouse   477 HSGFPSPSVA 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
padNP_650534.2 zf-AD 16..87 CDD:214871
C2H2 Zn finger 710..730 CDD:275368 3/19 (16%)
zf-C2H2 736..760 CDD:278523 10/23 (43%)
C2H2 Zn finger 738..760 CDD:275368 10/21 (48%)
zf-H2C2_2 752..777 CDD:290200 10/24 (42%)
zf-C2H2 766..788 CDD:278523 9/21 (43%)
C2H2 Zn finger 768..788 CDD:275368 9/19 (47%)
zf-H2C2_2 780..808 CDD:290200 10/27 (37%)
C2H2 Zn finger 799..819 CDD:275368 6/19 (32%)
Egr1NP_031939.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..94 21/86 (24%)
DUF3446 132..207 CDD:288757 18/76 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..237 16/75 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 316..336 4/24 (17%)
zf-C2H2 336..360 CDD:278523 10/23 (43%)
C2H2 Zn finger 338..360 CDD:275368 10/21 (48%)
zf-H2C2_2 352..377 CDD:290200 10/24 (42%)
COG5048 363..>421 CDD:227381 21/60 (35%)
C2H2 Zn finger 368..388 CDD:275368 9/19 (47%)
zf-H2C2_2 380..405 CDD:290200 10/27 (37%)
C2H2 Zn finger 396..416 CDD:275368 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 407..478 19/103 (18%)
DUF3432 426..520 CDD:288743 20/94 (21%)
BES1_N <441..478 CDD:283367 10/62 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.