DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pad and ZFP42

DIOPT Version :9

Sequence 1:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_001291287.1	Gene:	ZFP42 / 132625	HGNCID:	30949	Length:	310	Species:	Homo sapiens

Alignment Length:	183	Identity:	46/183 - (25%)
Similarity:	74/183 - (40%)	Gaps:	47/183 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   639 PVSVPALSQAQPPPLAAQHKKIVRKPPENQD--------------TSGQKVKAARPPQQILPSPQ 689
            |..:|.:..:.|..||...:|   |||.|::              |...:.:||.....::..|:
Human   154 PGGIPGIDLSDPKQLAEFARK---KPPINKEYDSLSAIACPQSGCTRKLRNRAALRKHLLIHGPR 215

  Fly   690 QEGQNATHSGSEAPTTSGLICPTCKREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKEHLS 754
            ..                 :|..|.:.|.:...|.:|..:|.|.:||:|:.|||.|.||...:|.
Human   216 DH-----------------VCAECGKAFVESSKLKRHFLVHTGEKPFRCTFEGCGKRFSLDFNLR 263

  Fly   755 RHLVSHSGQKMYTC--EVCKKPFSRKDNLNKHRRIHTQTSTETLYCCDVCNKN 805
            .|:..|:|:|.:.|  :.|.:.|.:.:||..|...|..|           |||
Human   264 THVRIHTGEKRFVCPFQGCNRRFIQSNNLKAHILTHANT-----------NKN 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	5/19 (26%)
		zf-C2H2	736..760	CDD:278523	10/23 (43%)
		C2H2 Zn finger	738..760	CDD:275368	9/21 (43%)
		zf-H2C2_2	752..777	CDD:290200	8/26 (31%)
		zf-C2H2	766..788	CDD:278523	6/23 (26%)
		C2H2 Zn finger	768..788	CDD:275368	6/21 (29%)
		zf-H2C2_2	780..808	CDD:290200	8/26 (31%)
		C2H2 Zn finger	799..819	CDD:275368	3/7 (43%)
ZFP42	NP_001291287.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		C2H2 Zn finger	190..212	CDD:275368	3/21 (14%)
		COG5048	214..>307	CDD:227381	33/120 (28%)
		C2H2 Zn finger	219..239	CDD:275368	5/19 (26%)
		zf-H2C2_2	232..257	CDD:290200	11/24 (46%)
		C2H2 Zn finger	247..269	CDD:275368	9/21 (43%)
		zf-H2C2_2	261..288	CDD:290200	8/26 (31%)
		C2H2 Zn finger	277..299	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000