DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pad and klf9

DIOPT Version :9

Sequence 1:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_001107146.1	Gene:	klf9 / 100134994	XenbaseID:	XB-GENE-483889	Length:	289	Species:	Xenopus tropicalis

Alignment Length:	367	Identity:	87/367 - (23%)
Similarity:	135/367 - (36%)	Gaps:	108/367 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 TTVTQNQFLAPQQPLTQLPNTAQVTSQQIIRSPHTSTTNSQLVIRNVTNIPPTPTTPTSSKKAPT 498
            |.|..:.|:| .|.|..:.|...|..|:.:..|..|..:|:          |||.      .:|.
Frog     2 TAVAYSDFVA-AQCLVSISNRKAVPPQEEVEGPLYSALDSR----------PTPA------HSPA 49

  Fly   499 FKTPS-PKQK-----PMPSPKSKTTVGPSSGGSNGTSTNEFKRLITQTKPQPQVKQQQTAGLSAS 557
            ....: |:|:     |.|.|..:...||      |.:..::..|:|..|...::.:.:
Frog    50 LHLRNMPEQEAALHLPEPGPNKEHHDGP------GEAWKDYCTLLTIAKSLLELNKYR------- 101

  Fly   558 GAPTATSANQAAMQRLSSNTTITKVPKQPASLPAPAPTSNPAKLPMLNKQNITISRISMQTAPKA 622
              |..:.|...:.:.|.|::.:|.......| |:.:|.|                 .|..|.|..
Frog   102 --PLPSPAYSHSDEELCSDSDVTTESGLSFS-PSHSPGS-----------------CSSSTTPSH 146

  Fly   623 QS---KPSTTSPTPASQPIPVSVPALSQAQPPPLAAQHKKIVRKPPENQDTSGQKVKAARPPQQI 684
            ..   :|.:|.|.|.:|..|.|...                    |..:||
Frog   147 MDYSPEPGSTQPLPLTQDAPKSPTR--------------------PLGKDT-------------- 177

  Fly   685 LPSPQQEGQNATHSGSEAPTTSGLICP--TCKREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTF 747
              :|.:......|.           ||  .|.:.:.|..||..|.::|.|.|||.|:...|.|.|
Frog   178 --APVRSTNEKRHR-----------CPYAGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKF 229

  Fly   748 SRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIHT 789
            ||.:.|:||..:|:|:|.:.|.:|:|.|.|.|:|.||.|.||
Frog   230 SRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHT 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	7/21 (33%)
		zf-C2H2	736..760	CDD:278523	10/23 (43%)
		C2H2 Zn finger	738..760	CDD:275368	9/21 (43%)
		zf-H2C2_2	752..777	CDD:290200	10/24 (42%)
		zf-C2H2	766..788	CDD:278523	10/21 (48%)
		C2H2 Zn finger	768..788	CDD:275368	10/19 (53%)
		zf-H2C2_2	780..808	CDD:290200	6/10 (60%)
		C2H2 Zn finger	799..819	CDD:275368
klf9	NP_001107146.1	SFP1	<184..272	CDD:227516	37/99 (37%)
		C2H2 Zn finger	190..212	CDD:275368	7/21 (33%)
		C2H2 Zn finger	220..242	CDD:275368	9/21 (43%)
		zf-H2C2_2	234..257	CDD:372612	9/22 (41%)
		C2H2 Zn finger	250..270	CDD:275368	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910