Protein Alignment CG17930 and MPH2

DIOPT Version :10

• Sequence 1: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_010034.1
• Gene: MPH2 / 851350
• SGDID: S000002406
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 553
• Identity: 103/553 - (18%)
• Similarity: 183/553 - (33%)
• Gaps: 177/553 - (32%)

  Fly    42 PPTTVIITTQSNSRWA---TPTQTQSGTAATLLFVYAGMDMAQ-GLG--------WNLTAVSANT 94
            |..|.:.|....:.|:   :.|....|....:|..:..:.:.| ..|        |.::|
Yeast    86 PLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISA----- 145

  Fly    95 LEFQYSWFIGVIIGAVVSAITSAFL--PKIVFYGLGGVMNLIDAIIFVSAPYEYESIL-AARYVG 156
                 ||.||:.:..:...|....|  |.:..  :|....||.|:.|::|   :..|| ....:|
Yeast   146 -----SWQIGLTLCYMAGEIVGLQLTGPSVDL--VGNRYTLIIALFFLAA---FTFILYFCNSLG 200

  Fly   157 GVGIG--LITVPF-------LIHSAEIAS------STNRGTCCALEQYGLALGVA--IQVIY-DS 203
            .:.:|  |..:|:       :.:::||..      .|.....|.|.....|.|:.  .|..| ||
Yeast   201 MIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADS 265

  Fly   204 QWSQGLGMTINRVHGIFGIVFTAIALGSVAITIDSPIFYIRQNQEQKARASVKQLM--------- 259
            :....|...:.      .|:...:||| :....:||.:.:::.:..:||.|:::.:
Yeast   266 ELGYKLPFALQ------WILPVPLALG-IFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEI 323

  Fly   260 -----------------------GSY-------------------WTREA--GDRAYDEAKLYVV 280
                                   |||                   |..:|  |.         ::
Yeast   324 LVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGS---------IL 379

  Fly   281 EGSAQGVGEQLGESMMPFLKLLLFRCFVAFTFSVPLSYSILTTTELVEGTLHSWPTIIFGLLRLI 345
            .|.:....|:.|.|..           ::||||: :.|.:    .:....|..|.:..||...|.
Yeast   380 IGYSTYFYEKAGVSTE-----------MSFTFSI-IQYCL----GICATFLSWWASKYFGRYDLY 428

  Fly   346 GALITFAVLDTVGRKFVSLLGLMCMA--GLMLGMAGVYGDYGHIFDDYFMWQVCRLGMAFQFFAG 408
            ...:.|..:     .|..:.||.|.:  |..:|...                   |.||..||..
Yeast   429 AFGLAFQTI-----VFFIIGGLGCSSTHGSKMGSGS-------------------LLMAVAFFYN 469

  Fly   409 FFICSSSAYLGEAFP---MRVKPFLIG-------LIVCLEQVIHIIVIVKFVPTAE--FYYTYFV 461
            ..|......|....|   :|.|..::.       .|:|...:::.:...|:...|:  |::
Yeast   470 LGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFW---- 530

  Fly   462 AVGIIMVIGLVAFAVLMPETRGLTLRQAGERFR 494
              |::....|:...|.:|||.|.|..:..|.|:
Yeast   531 --GVLCFCTLIWAVVDLPETAGKTFVEINELFK 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17930	NP_650533.1	MFS	98..488	CDD:475125	90/477 (19%)
MPH2	NP_010034.1	SP	72..556	CDD:273317	101/546 (18%)