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Protein Alignment CG17930 and SLC2A4

DIOPT Version :10

Sequence 1:	NP_650533.1	Gene:	CG17930 / 41979	FlyBaseID:	FBgn0038416	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001033.1	Gene:	SLC2A4 / 6517	HGNCID:	11009	Length:	509	Species:	Homo sapiens

Alignment Length:	532	Identity:	114/532 - (21%)
Similarity:	201/532 - (37%)	Gaps:	147/532 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 PTQTQSGTAATLLFVYAGMDMAQGLGWNLTAVSA--NTLEFQYS--------------------- 100
            |.|..:||  .:|.|::.:..:...|:|:..::|  ..:|..|:
Human    16 PQQRVTGT--LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLT 78

  Fly   101 --WFIGVIIGAVVSAITSAFLPKIVFYGLGG----VMNLIDAII------FVSAPYEYESILAAR 153
              |.:.|.|.: |..:.|:||..|:...||.    ::|.:.|::      ..:|...||.::..|
Human    79 TLWALSVAIFS-VGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGR 142

  Fly   154 YVGGVGIGLIT--VPFLIHSAEIASSTNRGTCCALEQYGLALGVAIQVIYD--------SQWSQG 208
            ::.|...||.:  ||..:  .|||.:..||....|.|..:.:|:.|..:..        |.|...
Human   143 FLIGAYSGLTSGLVPMYV--GEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLL 205

  Fly   209 LGMTINRVHGIFGIVFTAIALGSVAITIDSPIF-YIRQNQEQKARASVKQLMGSYWTREAGDRAY 272
            ||:|         ::...:.|..:....:||.: ||.||.|..||.|:|:|.|  |...:|..|.
Human   206 LGLT---------VLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTG--WADVSGVLAE 259

  Fly   273 ---DEAKLYVVEGSAQGVGEQLGESMMPFLKLLLFRCFVAFTFSVPLSYS-ILTTTELVEG--TL 331
               ::.||           |:  |..:..|:||..|     |...||..: :|..::.:.|  .:
Human   260 LKDEKRKL-----------ER--ERPLSLLQLLGSR-----THRQPLIIAVVLQLSQQLSGINAV 306

  Fly   332 HSWPTIIF---------------GLLRLIGALITFAVLDTVGRKFVSLLGL--MCMAGLMLGMA- 378
            ..:.|.||               |::..:..|::..:::..||:.:.||||  ||...:::.:|
Human   307 FYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVAL 371

  Fly   379 ---------------GVYGDYGHIFDDYFMWQVCRLGMAFQFFAGFFICSSSA----YLGEAFPM 424
                           .::|                       |..||......    .:.|.|..
Human   372 LLLERVPAMSYVSIVAIFG-----------------------FVAFFEIGPGPIPWFIVAELFSQ 413

  Fly   425 RVKPFLIGLIVCLEQVIHIIVIVKFVPTAEFYYTYFVAVGIIMVIGLVAFAVL-MPETRGLTLRQ 488
            ..:|..:.:........:.|:.:.|...||....|...:..::::|...|..| :|||||.|..|
Human   414 GPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQ 478

  Fly   489 AGERFRRVHDVM 500
            ....|.|...::
Human   479 ISAAFHRTPSLL 490

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.