Protein Alignment CG17930 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 108/504 - (21%)
• Similarity: 196/504 - (38%)
• Gaps: 97/504 - (19%)

  Fly    28 YITNGRQQQPP------PPPPPTTVIITTQSNSRWATPTQTQSGTAATLLFVYAGMDMAQGLGWN 86
            |:.|...:.|.      |.|.|            ||......:....|:|             |:
Human    59 YVINSTDELPTISYSMNPKPTP------------WAEEETVAAAQLITML-------------WS 98

  Fly    87 LT----AVSANTLEFQYSWFIGVIIGAVVSAITSAFLPKIVFYGLGGVMNLIDAII--FVSAPYE 145
            |:    ||...|..|...| :|..:|.:.:.:            :..:::|:.|::  |......
Human    99 LSVSSFAVGGMTASFFGGW-LGDTLGRIKAML------------VANILSLVGALLMGFSKLGPS 150

  Fly   146 YESILAARYVGGVGIGLIT--VPFLIHSAEIASSTNRGTCCALEQYGLALGVAIQVIYDSQWSQG 208
            :..|:|.|.:.|:..|||:  ||..|  .|||.:..||......|..:..|:.|..|...::..|
Human   151 HILIIAGRSISGLYCGLISGLVPMYI--GEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILG 213

  Fly   209 LGMTINRVHGIFGIVFTAIALGSVAITI--DSPIF-YIRQNQEQKARASVKQLMGSY-------- 262
               ..:..|.:.|:......|.|:.:..  :||.: ||:.::|.||:.|:|:|.| |
Human   214 ---NYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRG-YDDVTKDIN 274

  Fly   263 WTREAGDRAYDEAKLYVVEGSAQGVGEQLGESMMPFLKLLLFRCFVAFTFS-----VPLSYSILT 322
            ..|:..:.|..|.|:.:::........|      |.|..|:..  ||..||     ...|.||..
Human   275 EMRKEREEASSEQKVSIIQLFTNSSYRQ------PILVALMLH--VAQQFSGINGIFYYSTSIFQ 331

  Fly   323 TTELVEGTLHSWPTIIFGLLRLIGALITFAVLDTVGRKFVSLLGLMCMAGLMLGMAGVYGDYGHI 387
            |..:.:..   :.||..|.:.::...::..:::..||:.:.|:|   |:|:.  :..::...|.:
Human   332 TAGISKPV---YATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIG---MSGMF--VCAIFMSVGLV 388

  Fly   388 FDDYFMWQVCRLGMAFQFFAGFFICSSSA----YLGEAFPMRVKPFLIGLIVCLEQVIHIIVIVK 448
            ..:.|.|......:|...|..||......    .:.|.|....:|..:.:........:.||.:.
Human   389 LLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALC 453

  Fly   449 FVPTAEFY--YTYFVAVGIIMVIGLVAFAVLMPETRGLTLRQAGERFRR 495
            |...|:|.  |.:|:..|:::...|..| ..:|||:|.:..:....|::
Human   454 FQYIADFCGPYVFFLFAGVLLAFTLFTF-FKVPETKGKSFEEIAAEFQK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17930	NP_650533.1	MFS	98..488	CDD:475125	91/415 (22%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	106/491 (22%)