Protein Alignment CG17930 and SLC2A1

DIOPT Version :10

• Sequence 1: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 95/486 - (19%)
• Similarity: 184/486 - (37%)
• Gaps: 143/486 - (29%)

  Fly    84 GWNLTAVSANTLEFQYSWFIGVII----GAVVSAITSAFLPKIVFYGLGGVMNLIDAIIFVSAPY 144
            |.::...:..||     |.:.|.|    |.:.|.....|:.:   :|....|.:::.:.||||..
Human    53 GESILPTTLTTL-----WSLSVAIFSVGGMIGSFSVGLFVNR---FGRRNSMLMMNLLAFVSAVL 109

  Fly   145 --------EYESILAARYVGGVGIGLIT--VPFLIHSAEIASSTNRGTCCALEQYGLALGVAIQV 199
                    .:|.::..|::.||..||.|  ||..:  .|::.:..||....|.|.|:.:|:.|..
Human   110 MGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYV--GEVSPTALRGALGTLHQLGIVVGILIAQ 172

  Fly   200 IYDSQWSQGLGMTINRVHG-------IFGIVFTAIALGSVAITI--DSPIF-YIRQNQEQKARAS 254
            ::.          ::.:.|       :..|:|....|..:.:..  :||.| .|.:|:|.:|::.
Human   173 VFG----------LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSV 227

  Fly   255 VKQLMGSYWTREAGDRAYDEAKLYVVEGSAQGVGEQLGESMMPFLKLLLFRCFVAFTFSVPLSYS 319
            :|:|.|:      .|..:|..::           ::....||...|:.:...|.:..:..|:..:
Human   228 LKKLRGT------ADVTHDLQEM-----------KEESRQMMREKKVTILELFRSPAYRQPILIA 275

  Fly   320 -ILTTTELVEG--TLHSWPTIIF---------------GLLRLIGALITFAVLDTVGRKFVSLLG 366
             :|..::.:.|  .:..:.|.||               |::.....:::..|::..||:.:.|:|
Human   276 VVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIG 340

  Fly   367 LMCMAG----LMLGMAGVYGDYGHIFDDYFMWQVCRLGMAFQFFAGFFICSSSA----YLGEAFP 423
            |..|||    :.:.:|.:         :...|......:|...|..||......    .:.|.|.
Human   341 LAGMAGCAILMTIALALL---------EQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFS 396

  Fly   424 MRVKP--------------FLIGLIVCLEQV----------IHIIVIVKFVPTAEFYYTYFVAVG 464
            ...:|              |::|:  |.:.|          |..:::|.|     |.:|||
Human   397 QGPRPAAIAVAGFSNWTSNFIVGM--CFQYVEQLCGPYVFIIFTVLLVLF-----FIFTYF---- 450

  Fly   465 IIMVIGLVAFAVLMPETRGLTLRQAGERFRR 495
                        .:|||:|.|..:....||:
Human   451 ------------KVPETKGRTFDEIASGFRQ 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17930	NP_650533.1	MFS	98..488	CDD:475125	90/463 (19%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	91/473 (19%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		1/2 (50%)