Protein Alignment CG17930 and SLC2A8

DIOPT Version :10

• Sequence 1: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_047279239.1
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 599
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 111/563 - (19%)
• Similarity: 215/563 - (38%)
• Gaps: 146/563 - (25%)

  Fly    10 PVPVQQTTYITTGPQQTTY-------------ITNGRQQQPPPPPPPTTVIITTQSNSRWATPTQ 61
            |.|..|    .:||..||:             :.:||...|..|.||    :.|.:..  .:|..
Human   101 PFPSGQ----ASGPAATTFPHETGIGPLCPPSLPSGRASSPSAPTPP----LGTSTGP--LSPLP 155

  Fly    62 TQSGTAATLLFVYAGMDMAQGLGWNLTAVSANTLEFQYSW--FIGVIIGAVVSAITSAFLPKIVF 124
            ..||             .|:|.| :.|:..|.:     .|  .:|...||..||  :|.|..:|.
Human   156 LPSG-------------RARGPG-SFTSEPAGS-----GWRGRMGCGFGAPSSA--AARLQAVVT 199

  Fly   125 YG--LGGVMN--LID------AIIFVSAPY-----------EYESILAARYVGGVGIGLITVPFL 168
            .|  .|||:.  |:|      :::..|.|:           :...:|..|.:.|:..|:.::...
Human   200 LGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAP 264

  Fly   169 IHSAEIASSTNRGTCCALEQYGLALGVAIQVI--YDSQWSQGLGMTINRVHGIFGIVFTAIALGS 231
            ::.:|||....||...:..|..:.:|:.:..:  :..:|         |...:.|.|..::.|..
Human   265 VYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEW---------RWLAVLGCVPPSLMLLL 320

  Fly   232 VAITIDSPIFYIRQNQEQKARASVKQLMGSYWTREAGDRAYDEAKLYVVEGSAQ----------G 286
            :....::|.|.:.|::.|:|.|:::.|.||       ::.:::..:    |:.|          |
Human   321 MCFMPETPRFLLTQHRRQEAMAALRFLWGS-------EQGWEDPPI----GAEQSFHLALLRQPG 374

  Fly   287 VGEQ--LGESMMPFLKLLLFRCFVAFTFSVPLSYSILTTTELVEGTLHSWPTIIFGLLRLIGALI 349
            :.:.  :|.|:|.|.:|......:.:      :.:|....:..:.:|.|   ::.|:::::...:
Human   375 IYKPFIIGVSLMAFQQLSGVNAVMFY------AETIFEEAKFKDSSLAS---VVVGVIQVLFTAV 430

  Fly   350 TFAVLDTVGRKFVSLLGLMCMAGLMLGMA----GVY--------GDYGHIFDDY----------- 391
            ...::|..||:.     |:.::|:::..:    |.|        |:..|:....
Human   431 AALIMDRAGRRL-----LLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASV 490

  Fly   392 -FMWQVCRLGMAFQFFAGFFICSSS---AYLGEAFPMRVKPFLIGLIVCLEQVIHIIVIVKFVPT 452
             ..|  ..:|....|.|||.:....   ..:.|.||:.||....|:.|....::..:|..:|...
Human   491 GLAW--LAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSL 553

  Fly   453 AEFYYTY--FVAVGIIMVIGLVAFAVLMPETRGLTLRQAGERF 493
            .|....|  |.......:..::.....:|||:|.||.|....|
Human   554 MEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHF 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17930	NP_650533.1	MFS	98..488	CDD:475125	87/455 (19%)
SLC2A8	XP_047279239.1	PHA03307	3..>196	CDD:223039	30/125 (24%)
		MFS	36..591	CDD:475125	109/556 (20%)