Protein Alignment CG17930 and hmit-1.1

DIOPT Version :10

• Sequence 1: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 94/559 - (16%)
• Similarity: 191/559 - (34%)
• Gaps: 160/559 - (28%)

  Fly    71 LFVY--AGMDMAQG--LGWNLTAVSANTL----------------EFQYSWFIGV-IIGAVVSAI 114
            ||||  |...:..|  .|::.:.|||..|                |...|...|: .:|:::|..
 Worm    23 LFVYILAAASVIGGFLFGYDTSVVSAAMLYMPDAPGLKPMDTVWQEVLVSISPGMAAVGSLMSGT 87

  Fly   115 TSAFL-PKIVFYGLGGVMNLIDAIIFVSAPYEYESILAARYVGGVGIGLITVPFLIHSAEIASST 178
            :|.:: .:.|..|...:.. |.|:: .:|......:|..|.:.|:.||..::...::..|.|.:.
 Worm    88 SSDYIGRRKVILGASAIFT-IGALV-CAASVNKIMLLVGRVLLGIAIGFASMIVPVYLGETAPTH 150

  Fly   179 NRGTCCALEQYGLALGVAIQVI----------YDSQWSQGLGMTINRVHGIFGIVFTAIALGSVA 233
            .||...|.....::.|..:..|          |:..|         |:...|..|.:.|......
 Worm   151 VRGMLVAAFALMISFGQVVANITGGAFSYIDPYNVGW---------RLMFAFAAVPSIIQFVCFM 206

  Fly   234 ITIDSPIFYIRQNQEQKARASVKQLMGSYWTREAGDR---AYDEAKLYVVEGSAQGVGEQL---G 292
            ...::|.:......|.:.|..::::..       ||:   .|:.|::...........|:.   |
 Worm   207 FLPETPRWLYENGFETETREVLEKVYN-------GDKEWVEYEMAEIIAFNEDQAKENEKAHASG 264

  Fly   293 ESMMPFLKL--LLFRCFV-----AFTFSVPLSYSILTTTELVEGTLHS------WPTIIFGLLRL 344
            ..:...||.  :|..||:     ||.....::..:..|.:::..:..|      |.:::..|...
 Worm   265 PVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNNHTTIWISVLLSLCNF 329

  Fly   345 IGALITFAVLDTVGRKFVSLL--GLMCMAGLMLGMAGVY-----------GDYGHIFD------- 389
            ||..:..::::.|||:.:.|.  ||:.::.:.:|:|.:.           ..||..|:
 Worm   330 IGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFIGVAFLLVNHDSAATLPANQYGSNFNSSYPDAK 394

  Fly   390 --------DY-----------------------------------------------FMWQ---- 395
                    ||                                               |.|:
 Worm   395 GCMAYSNCDYCVTTDACGFCHDANTKQGYCLPAGFDNPEVYSSTGSCTNSNGSIANNFKWEKYYC 459

  Fly   396 --------VCRLGMAFQFFAGFFICSSSAYLGEAFPMRVKPFLIGLIVCLEQVIHIIVIVKFVPT 452
                    :...|:....|:..|.........|.:||..:...:.:......|.::|:.:.::..
 Worm   460 DTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNWVFNLIIALTYLSL 524

  Fly   453 AEF---YYTYFVAVGIIMVIGLVAFAVLMPETRGLTLRQ 488
            .:.   |..:::..| :.||..:....|:|||:|.::.:
 Worm   525 TQVIGKYGAFWLYAG-LTVIAFIFILFLVPETKGYSIEE 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17930	NP_650533.1	MFS	98..488	CDD:475125	82/510 (16%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	85/541 (16%)