Protein Alignment CG17930 and SLC2A12

DIOPT Version :10

• Sequence 1: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_660159.1
• Gene: SLC2A12 / 154091
• HGNCID: 18067
• Length: 617
• Species: Homo sapiens
• Alignment Length: 645
• Identity: 119/645 - (18%)
• Similarity: 222/645 - (34%)
• Gaps: 232/645 - (35%)

  Fly    11 VPVQQTTYITTGP----QQTTYI-TNGRQQQPPPPPPPTTVIITTQSNSRWATP----TQTQSGT 66
            |||:.    |.||    |:.|.: |.|...:.||                ||..    |...|.|
Human     2 VPVEN----TEGPSLLNQKGTAVETEGSGSRHPP----------------WARGCGMFTFLSSVT 46

  Fly    67 AATLLFVYAGMDMAQGLG---------WNLTAVSANTLEFQYSWFIGVIIGAVVSAIT------- 115
            ||.     :|:.:...||         ..|.|:|.:..|...|   .::|||:::::|
Human    47 AAV-----SGLLVGYELGIISGALLQIKTLLALSCHEQEMVVS---SLVIGALLASLTGGVLIDR 103

  Fly   116 ----SAFLPKIVFYGLGGVMNLIDAIIFVSAPYEYESILAARYVGGVGIGLITVPFLIHSAEIAS 176
                :|.:......|||.::.::.        ..|..::..|...||.|.|.::...::.||||.
Human   104 YGRRTAIILSSCLLGLGSLVLILS--------LSYTVLIVGRIAIGVSISLSSIATCVYIAEIAP 160

  Fly   177 STNRGTCCALEQYGLALGVAIQVIYDSQWSQGLGMTINRVHG---IFGIVFTAIALGSVAITI-- 236
            ...||...:|.:..:.:|:....|.:..::       |..||   :||:|.....|.::|:..
Human   161 QHRRGLLVSLNELMIVIGILSAYISNYAFA-------NVFHGWKYMFGLVIPLGVLQAIAMYFLP 218

  Fly   237 DSPIFYIRQNQEQKA--------------------RASVK-QLMGSYWTREAGD--RAYDEAKLY 278
            .||.|.:.:.||..|                    ::|:| :...|:|     |  |:.|..:..
Human   219 PSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFW-----DLFRSKDNMRTR 278

  Fly   279 VVEGSAQGVGEQLGESMMPFLKL-----LLFRCFVAFTFSVPLSYSILTTTELVEGTLHSWPTII 338
            ::          :|.:::.|:::     :||           .:.::|.:.........|..:..
Human   279 IM----------IGLTLVFFVQITGQPNILF-----------YASTVLKSVGFQSNEAASLASTG 322

  Fly   339 FGLLRLIGALITFAVLDTVGRKFVSLLGLMCMAGLMLGMA----GVYGDYGHI------------ 387
            .|::::|..:....::|.||.|....:|...||..::.|.    .::.::.||
Human   323 VGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLD 387

  Fly   388 ----------------FDDYFMW-------------------------QVCRLGMA---FQ---- 404
                            ..|:|..                         .:...|::   :|
Human   388 ESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTD 452

  Fly   405 ------FFAGFFICSSSAY---------------LGEAFPMRVKPFLIGLIVCLEQVIHIIVIVK 448
                  |.....:.|...|               |.|.||..::...:.|...:...|::::.:.
Human   453 PGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLT 517

  Fly   449 F--------VPTAEFYYTYFVAVGIIMVIGLVAFAVL-MPETRGLTLRQAGERFRRVHDV 499
            |        :|...|.||       ||.:..:.|.|: :|||:|.:|.|......:|:.|
Human   518 FLTVTDLIGLPWVCFIYT-------IMSLASLLFVVMFIPETKGCSLEQISMELAKVNYV 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17930	NP_650533.1	MFS	98..488	CDD:475125	90/527 (17%)
SLC2A12	NP_660159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		10/30 (33%)
		MFS_GLUT12_Class3	42..560	CDD:340993	101/573 (18%)