Protein Alignment CG17929 and ITR1

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 514
• Identity: 94/514 - (18%)
• Similarity: 186/514 - (36%)
• Gaps: 129/514 - (25%)

  Fly     3 IAYVTAGPDPSPTKDYAEGYKPNI--------PSREPSIQINSSTSN--PGS-------VRQINK 50
            |.|:|:....|...| |.|...::        ||:...|.:.|....  |.|       ::.:|.
Yeast     5 IPYLTSKTSQSNVGD-AVGNADSVEFNSEHDSPSKRGKITLESHEIQRAPASDDEDRIQIKPVND 68

  Fly    51 Q--------INVACAVF-----FLYVYGGMDFAHSAGW-------------NQTLNTTATQVFKC 89
            :        .|.:.:.|     |:....|..|.:..|:             ::.|.....::...
Yeast    69 EDDTSVMITFNQSLSPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTA 133

  Fly    90 SWFIGVLAGAALASLTMTFLPKLP-------FYVLGGLMQLTGSIIFTCKPFDYGCLLAARYVAG 147
            :..:|.|..:..|........:..       .:|:|.::|::....:.        :...|.:.|
Yeast   134 ATSLGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQ--------MAVGRLIMG 190

  Fly   148 AGIGL--ITVPFLIHSAEVATDNHRG---VSGSMEQCG---LALGIAIQVIYDTQWVDDKEASVN 204
            .|:|:  :..|..|  :|:|....||   |..|:...|   :|.|..              |.:|
Yeast   191 FGVGIGSLIAPLFI--SEIAPKMIRGRLTVINSLWLTGGQLVAYGCG--------------AGLN 239

  Fly   205 EVHG----IIGIVFSIIGLGMTALSI--ESPIYYLRIKQKEKARKCHAKLLGSFNHS----VDQE 259
            .|:.    ::|:......:..|.|..  ::|.||  :.:.:.||.... |..|:..:    ::::
Yeast   240 YVNNGWRILVGLSLIPTAVQFTCLCFLPDTPRYY--VMKGDLARATEV-LKRSYTDTSEEIIERK 301

  Fly   260 FEEI--------------QLYVAESQKRTFCQELRISVVPFIKLLLYRGFVAFSFSLPLSESLIK 310
            .||:              :::....:..|....||..::. ..|...:.|..::..:..|.::.:
Yeast   302 VEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNLRALIIG-CGLQAIQQFTGWNSLMYFSGTIFE 365

  Fly   311 SALLTEGF--ISCWPVTVWGLVRLLGALVAQGFLDKLGRKFVSLVGL--LCMAILMLCMAASYA- 370
                |.||  .|...:.|.| ...:..|||...:||:||:.:.|:||  :.||:::..:|..:.
Yeast   366 ----TVGFKNSSAVSIIVSG-TNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLG 425

  Fly   371 ---NPANALMTYYMYQVWRLG-----LAFQAFAGLFVCSSSVYLGEAFPIKVKPFFVGY 421
               :.|.|::....:..|.:.     :.|.||..|.:.:......|.||..|:.....|
Yeast   426 IKFDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYALGIGTVPWQQSELFPQNVRGIGTSY 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	73/384 (19%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	77/426 (18%)