Protein Alignment CG17929 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 110/522 - (21%)
• Similarity: 191/522 - (36%)
• Gaps: 121/522 - (23%)

  Fly     5 YVTAGPDPSPTKDYAEGYKPNIPSREPSIQINSSTSNPGSVRQINKQINVACAVFFLYVYGGMDF 69
            ||....|..||..|:...||...:.|.::         .:.:.|....:::.:.|   ..|||..
Human    59 YVINSTDELPTISYSMNPKPTPWAEEETV---------AAAQLITMLWSLSVSSF---AVGGMTA 111

  Fly    70 AHSAGWNQTLNTTATQVFKCSWFIGVLAGAALASLTMTFLPKLPFYVLGGLMQLTGSIIFTCKPF 134
            :...||   |..|..:: |......:|  :.:.:|.|.|....|.::|
Human   112 SFFGGW---LGDTLGRI-KAMLVANIL--SLVGALLMGFSKLGPSHIL----------------- 153

  Fly   135 DYGCLLAARYVAGAGIGLIT--VPFLIHSAEVATDNHRGVSGSMEQCGLALGIAI-QVI------ 190
                ::|.|.::|...|||:  ||..|  .|:|....||..|:..|..:..||.| |:|
Human   154 ----IIAGRSISGLYCGLISGLVPMYI--GEIAPTALRGALGTFHQLAIVTGILISQIIGLEFIL 212

  Fly   191 --YDTQWVDDKEASVNEVHGIIGI--VFSIIGLGMTALSIESPIY-YLRIKQKEKARKCHAKLLG 250
              ||. |           |.::|:  |.:|:...:.....|||.| |:::.::.||::...:|.|
Human   213 GNYDL-W-----------HILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRG 265

  Fly   251 ------SFNH--------SVDQEFEEIQLYVAESQKRTFCQELRISVVPFIKLLLYRGFVAFSFS 301
                  ..|.        |.:|:...|||:...|.::.....|.:.|......:  .|...:|.|
Human   266 YDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGI--NGIFYYSTS 328

  Fly   302 LPLSESLIKSALLTEGFISCWPVTVWGLVRLLGALVAQGFLDKLGRKFVSLVGLLCMAILMLCMA 366
            :..:..:.|....|.|.         |.|.::...|:...::|.||:.:.|:|:..|.:..:.|:
Human   329 IFQTAGISKPVYATIGV---------GAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMS 384

  Fly   367 ASYANPANALMTYYMYQVWRLGLAFQAFAGLFVCSSSVYLGEAFPIKVKPFFVGYIIGFEQTIHI 431
            ...     .|:..:.:..:...:|...|...|         |..|..:..|.|............
Human   385 VGL-----VLLNKFSWMSYVSMIAIFLFVSFF---------EIGPGPIPWFMVAEFFSQGPRPAA 435

  Fly   432 INIVGYNKGYENFF--------------YHYYLSVGIILLVGVVFFGIVIPETKKTTLREATKLF 482
            :.|..::....||.              |.::|..| :||...:|....:||||..:..|....|
Human   436 LAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAG-VLLAFTLFTFFKVPETKGKSFEEIAAEF 499

  Fly   483 QR 484
            |:
Human   500 QK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	88/428 (21%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	107/509 (21%)