Protein Alignment CG17929 and SLC2A1

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 103/494 - (20%)
• Similarity: 194/494 - (39%)
• Gaps: 116/494 - (23%)

  Fly    63 VYGGMDFAHSAG------------WNQT---------LNTTATQVFKCS---WFIGVLAGAALAS 103
            |.|.:.|.::.|            :|||         |.||.|.::..|   :.:|.:.|:....
Human    20 VLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVG 84

  Fly   104 L---------TMTFLPKLPFY--VLGGLMQLTGSIIFTCKPFDYGCLLAARYVAGAGIGLIT--V 155
            |         :|..:..|.|.  ||.|..:|..|         :..|:..|::.|...||.|  |
Human    85 LFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKS---------FEMLILGRFIIGVYCGLTTGFV 140

  Fly   156 PFLIHSAEVATDNHRGVSGSMEQCGLALGIAIQVIYDTQWVDDKEASVNEVHG-------IIGIV 213
            |..:  .||:....||..|::.|.|:.:||.|..::          .::.:.|       ::.|:
Human   141 PMYV--GEVSPTALRGALGTLHQLGIVVGILIAQVF----------GLDSIMGNKDLWPLLLSII 193

  Fly   214 F--SIIGLGMTALSIESPIYYLRIKQKE-KARKCHAKLLGSFNHSVD-QEFEEIQLYVAESQKRT 274
            |  :::...:.....|||.:.|..:.:| :|:....||.|:.:.:.| ||.:|        :.|.
Human   194 FIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKE--------ESRQ 250

  Fly   275 FCQELRISVVPFIKLLLYRGFVAFSFSLPLSESL--------IKSALLTEGFISCWPV--TVW-G 328
            ..:|.:::::...:...||..:..:..|.||:.|        ..:::..:..:. .||  |:. |
Human   251 MMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ-QPVYATIGSG 314

  Fly   329 LVRLLGALVAQGFLDKLGRKFVSLVGLLCMAILMLCMAASYANPANALMTYYMYQVWRLGLAFQA 393
            :|.....:|:...:::.||:.:.|:||..||...:.|..     |.||:....:..:...:|...
Human   315 IVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI-----ALALLEQLPWMSYLSIVAIFG 374

  Fly   394 FAGLFVCSSSVYLGEAFPIKVKPFFVGYIIGFEQTIHIINIVGYNKGYENFF----YHY------ 448
            |...|         |..|..:..|.|..:.........|.:.|::....||.    :.|
Human   375 FVAFF---------EVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCG 430

  Fly   449 ---YLSVGIILLVGVVFFGIVIPETKKTTLREATKLFQR 484
               ::...::|::..:|....:||||..|..|....|::
Human   431 PYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	90/437 (21%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	100/481 (21%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		0/2 (0%)