Protein Alignment CG17929 and hmit-1.2

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_507624.1
• Gene: hmit-1.2 / 180206
• WormBaseID: WBGene00013074
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 105/587 - (17%)
• Similarity: 187/587 - (31%)
• Gaps: 206/587 - (35%)

  Fly    88 KCSWFIGVLAGAAL------------ASLTMTFLPKLP-------------------FYVLGGLM 121
            |..:|:.:|..||:            .|..|.::|:.|                   ...:|...
 Worm    21 KLGFFVYLLGSAAIIGGFLFGYDTSVVSAAMLYVPEAPGLKPMGTVWKEVIVSITPGMAAVGAWF 85

  Fly   122 QLTGSIIFTCKPFDYG-----------C--------LLAARYVAGAGIGLITVPFLIHSAEVATD 167
            ...||..:..||...|           |        :|..|...|.|||..::...::..|.:..
 Worm    86 SGAGSDRYGRKPIIIGSTLIFVCGAVICAVAWTKIVMLIGRIFLGVGIGFASMVVPVYLGEASPT 150

  Fly   168 NHRGVSGSMEQCGLALGIAIQVIYDTQWVDDKEASVNEVHGIIGIVFS-----IIG-------LG 220
            :.||.        |....|:.:.:.           ..|..|:|.|||     .||       .|
 Worm   151 HVRGT--------LVSAFAMMISFG-----------QVVANIMGGVFSYWEPYTIGWRLMFAFAG 196

  Fly   221 MTAL--------SIESPIYYLRIKQKEKARKCHAKLLGSFNHSVDQEFEEIQLYVAESQKRTFCQ 277
            :.||        ..|:|.:.......|:|.:...|:.|.....::.|..||:.|..|.||:...:
 Worm   197 IPALIQFVCFIFLPETPRWLYENGHTEQAEQVLEKIYGGNTEWIEYELAEIKTYAEERQKQMEEE 261

  Fly   278 E------LRISVVPFIKLLLYRGFVAFSFS--------LPLSESLIKSALLTEGFISCWPVTVWG 328
            :      .||...|.:....:.|.:..:|.        |..:..:|:||.:.......|...:..
 Worm   262 KKSGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSAGIENYHTIIWISVILS 326

  Fly   329 LVRLLGALVAQGFLDKLGRK----------FVSLVGLLCMAILML-------------CMAASYA 370
            :..|:|......|::||||:          .|||| |:.::.|::             .:|.:|.
 Worm   327 ICNLIGPFAPMFFIEKLGRRKLFLFSCAGVVVSLV-LIGVSFLLVGNDSAPNFDRSAYLLAGNYQ 390

  Fly   371 NPANA---LM----------------------TYYMYQVWRLGLAFQAFAGLFVCSSSV-YLGEA 409
            :...|   ||                      |.:...|....:...:..||  |::.: ....:
 Worm   391 SNGEAESCLMLSNCDSCVTSEHCGFCEDSETRTGFCLPVDHNDVTLYSSTGL--CTNGLDKSNSS 453

  Fly   410 FP---------------------IKVKPFFVGYIIGFEQTIHIINIVGYN----------KGYEN 443
            ||                     :.:..:.:.:..||.....::|...|.          ....|
 Worm   454 FPNATSYVWQKHHCTTSYTILPIVMMGVYLLTFSCGFTSLPWVLNSEFYPMWARSTCVSISTLSN 518

  Fly   444 FFYHY-----YLSV-------------GIILLVGVVFFGIVIPETKKTTLREATKLF--QRLQNI 488
            :.::.     |||:             .|..::..:|...::|||...::.|...||  :|.:||
 Worm   519 WVFNLIIALTYLSLTHAITKYGAFWLYAIFTIIAFIFIYFLVPETTGYSIDEVEMLFMNKRQRNI 583

  Fly   489 RL 490
            .:
 Worm   584 AM 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	98/568 (17%)
hmit-1.2	NP_507624.1	MFS	32..562	CDD:475125	93/551 (17%)