Protein Alignment CG17929 and hmit-1.1

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_507623.1
• Gene: hmit-1.1 / 180205
• WormBaseID: WBGene00013073
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 103/610 - (16%)
• Similarity: 184/610 - (30%)
• Gaps: 211/610 - (34%)

  Fly    54 VACAVFFLYVYGGMDFAHSAGWNQTLNTTATQVFKCSWFIGVLAGA------------ALASLTM 106
            ||.|.|           .|:|.::..:|.     |...|:.:||.|            ::.|..|
 Worm     2 VAVAAF-----------SSSGQDKPAHTP-----KLGLFVYILAAASVIGGFLFGYDTSVVSAAM 50

  Fly   107 TFLPKLP-------------------FYVLGGLMQLTGS--------IIFTCKPFDYGCLLAA-- 142
            .::|..|                   ...:|.||..|.|        |:.....|..|.|:.|
 Worm    51 LYMPDAPGLKPMDTVWQEVLVSISPGMAAVGSLMSGTSSDYIGRRKVILGASAIFTIGALVCAAS 115

  Fly   143 ---------RYVAGAGIGLITVPFLIHSAEVATDNHRGVSGSMEQCGLALGIAI-QVI------- 190
                     |.:.|..||..::...::..|.|..:.||    |.....||.|:. ||:
 Worm   116 VNKIMLLVGRVLLGIAIGFASMIVPVYLGETAPTHVRG----MLVAAFALMISFGQVVANITGGA 176

  Fly   191 ------YDTQWVDDKEASVNEVHGIIGIVFSIIGLGMTALSIESPIYYLRIKQKEKARKCHAKLL 249
                  |:..|         .:......|.|||.........|:|.:......:.:.|:...|:.
 Worm   177 FSYIDPYNVGW---------RLMFAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLEKVY 232

  Fly   250 GSFNHSVDQEFEEIQLY----VAESQKRTFCQEL--RISVVPFIKLLLYRGFVAFSFS------- 301
            ......|:.|..||..:    ..|::|......:  ||...|.:....:.|.:..:|.
 Worm   233 NGDKEWVEYEMAEIIAFNEDQAKENEKAHASGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINT 297

  Fly   302 -LPLSESLIKSALLTEGFISCWPVTVWGLVRLLGALVAQGFLDKLGRKFVSL--VGLLCMAILML 363
             |..:..:|:|:.::....:.|...:..|...:|..|....::|:||:.:.|  .||:.::::.:
 Worm   298 ILYYTADIIRSSGISNNHTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFLFSCGLVVLSLVFI 362

  Fly   364 -------------------------------------------------------------CMAA 367
                                                                         |:.|
 Worm   363 GVAFLLVNHDSAATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCHDANTKQGYCLPA 427

  Fly   368 SYANP----------------ANAL--------MTYYMYQVWRLGLAFQAFAGLFVCSSSVYLGE 408
            .:.||                ||..        ..|.:..:...|:....|:..|.....|...|
 Worm   428 GFDNPEVYSSTGSCTNSNGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSE 492

  Fly   409 AFPIKVKPFFVGYIIGFEQTIHII---------NIVGYNKGYENFFYHYYLSVGIILLVGVVFFG 464
            .:|:..:...|..........::|         .::|   .|..|:.:..|:|     :..:|..
 Worm   493 FYPMWARSTCVAISTTSNWVFNLIIALTYLSLTQVIG---KYGAFWLYAGLTV-----IAFIFIL 549

  Fly   465 IVIPETKKTTLREATKLFQRLQNIR 489
            .::||||..::.|...||...:..|
 Worm   550 FLVPETKGYSIEEVEMLFMNKKQRR 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	91/560 (16%)
hmit-1.1	NP_507623.1	MFS_HMIT_like	31..554	CDD:340918	84/543 (15%)