Protein Alignment CG17929 and hmit-1.3

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 617
• Identity: 106/617 - (17%)
• Similarity: 197/617 - (31%)
• Gaps: 172/617 - (27%)

  Fly     3 IAYVTAGPDPSPTKDYAEGYKPNIPSREPSIQINSSTSNPGSVRQINKQINVACAVFFLY----- 62
            :|.|.||.....|:          ||.:|.                        ..:|:|
 Worm     4 VAPVAAGAGSGQTR----------PSSDPK------------------------TGWFVYMLAFS 34

  Fly    63 -VYGGMDFAH-----SAGWNQTLNTTATQVFKCSW---FIGVLAG-AALASLT----MTFLPKLP 113
             |.||..|.:     ||......|.:..:.....|   .:.:..| ||:.||.    ..||.:..
 Worm    35 AVIGGFLFGYDTGIVSAAMLYVPNASGIKPLDSVWQEIIVSITPGVAAIGSLCSGPGSDFLGRKK 99

  Fly   114 FYVLGGLMQLTGSIIFTCKPFDYGCLLAARYVAGAGIGLITVPFLIHSAEVATDNHRGVSGSMEQ 178
            . ::|..:..|...|.....:....||..|.:.|..||..::...|:.:|.:..:.||...:..|
 Worm   100 I-IIGASVTFTIGAIICAAAWTKIILLIGRILLGLAIGFASMIVPIYVSEASPSHIRGKLVTGFQ 163

  Fly   179 CGLALGIAIQVIYD--TQWVDDKEASVNEVHGIIGIVFSIIGLGMTALSIESPIYYLRIKQKEKA 241
            ..:.:|:.|..|..  ..:||..:.....:.....:. :||.........|||.:.....:..:|
 Worm   164 LMITVGLVIANIIGGAFSYVDPDQVGWRLMFAFAAVP-AIIQFVCFLFLPESPRWLYEHGRTVEA 227

  Fly   242 RKCHAKLLGSFNHSVDQEFEEIQLYVAESQKRTFCQE-------LRISVVPFIK--------LLL 291
            |:...::.......||.|..||. :..|.:.|...:.       :||...|.::        |.:
 Worm   228 REVLTRIYNGHTEWVDYEINEIS-FSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQM 291

  Fly   292 YRGFVAFSFSLPLSESLIKSALLTEGFISCWPVTVWGLVRLLGALVAQGFLDKLGRKFVSLVGLL 356
            ::.....:..:..:.::|:||.:.:...:.|.......:..||..:....::::||:.:.||.::
 Worm   292 FQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMI 356

  Fly   357 CMAILMLCMAASYANPANALMTYYMYQVWRLG--------------------------------- 388
            .:.:.::.|..|:....|..:..:..|.:.|.
 Worm   357 GVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGFCESKV 421

  Fly   389 ------LAFQA-----FAGLFVCSSS-------------VYLGEAF---PIKVKPFF-VGYIIGF 425
                  |.|.:     ::...:|..|             .|....|   ||.:..|: :.:..|:
 Worm   422 AKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTDFEWEDTYCHTKFTVLPIIIMVFYLLSFSAGY 486

  Fly   426 EQTIHIINIVGY---------------------------------NKGYENFFYHYYLSVGIILL 457
            .....::|...|                                 ...|..||  .|....::.|
 Worm   487 APLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFF--IYCGCTMVAL 549

  Fly   458 VGVVFFGIVIPETKKTTLREATKLFQRLQNIR 489
            |.|.||   :||||..::.|...||...:..|
 Worm   550 VFVFFF---VPETKGYSIDEVEMLFMTKEERR 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	85/505 (17%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:475125	88/531 (17%)
		MFS	<190..>249	CDD:475125	10/59 (17%)