Protein Alignment CG17929 and SLC2A14

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 109/520 - (20%)
• Similarity: 201/520 - (38%)
• Gaps: 113/520 - (21%)

  Fly    36 NSSTS------NPGSVRQINKQINVACAVFFLYVYGGMDFAHSAG------------WNQTLNTT 82
            :|.||      |.|...::...:..|..|..:   |...|.::.|            .|:||...
Human    27 SSQTSTLEKSQNGGVGEEVTPALIFAITVATI---GSFQFGYNTGVINAPETIIKEFINKTLTDK 88

  Fly    83 A---------TQVFKCS---WFIGVLAGAALASLTMTFLPKLPFYVLGGLMQLTGSIIF-TCKPF 134
            |         |.::..|   :.:|.:.|:....|.:....:....::..|:..||..:. .||..
Human    89 ANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIA 153

  Fly   135 D-YGCLLAARYVAGAGIGLIT--VPFLIHSAEVATDNHRGVSGSMEQCGLALGIAIQVIYDTQWV 196
            : ...|:..|.|.|...||.|  ||..|  .|::....||..|::.|.|:.:||.:..|:..:.:
Human   154 ESVEMLILGRLVIGLFCGLCTGFVPMYI--GEISPTALRGAFGTLNQLGIVIGILVAQIFGLELI 216

  Fly   197 DDKEASVNEVHGIIGIVFSIIGLGMTALSI----ESPIYYL-RIKQKEKARKCHAKLLGSFNHSV 256
            ...|    |:..:: :.|:|:...:.:.::    |||.:.| ..|::|.|.:...:|.|:  ..|
Human   217 LGSE----ELWPVL-LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGT--QDV 274

  Fly   257 DQEFEEIQLYVAESQKRTFCQELRISVVPFIKLLLYRGFVAFSFSLPLSESL------------- 308
            .|:.:|:     :.:.....||.:::|:...::..||..:..|..|.||:.|
Human   275 SQDIQEM-----KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGI 334

  Fly   309 IKSALLTE---GFISCWPVTVWGLVRLLGALVAQGFLDKLGRKFVSLVGLLCMAILMLCMAASYA 370
            .|.|.:.:   ..||.      |:|..:..|::...:::.||:.:.::||..||.....|..|.
Human   335 FKDAGVQQPIYATISA------GVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL- 392

  Fly   371 NPANALMTYYMYQVWRLGLAFQAFAGLFVCSSSVYLGEAFPIKVKPFFVGYIIGFEQTIHIINIV 435
                .|..:|.      |::|.....:.|..:...:|   |..:..|.|..:.........:.:.
Human   393 ----LLKNHYN------GMSFVCIGAILVFVACFEIG---PGPIPWFIVAELFSQGPRPAAMAVA 444

  Fly   436 GYNKGYENFFY-------HYYLSVGIILLVGVVFFGIVI----------PETKKTTLREATKLFQ 483
            |.:....||..       .|||..    .|.::|.|.:|          |||:..|..:.|:.|:
Human   445 GCSNWTSNFLVGLLFPSAAYYLGA----YVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE 505

  Fly   484  483
            Human   506  505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	92/431 (21%)
SLC2A14	NP_001273166.1	MFS_GLUT_Class1	51..495	CDD:340989	101/484 (21%)