Protein Alignment CG17929 and SLC2A13

DIOPT Version :10

• Sequence 1: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_443117.3
• Gene: SLC2A13 / 114134
• HGNCID: 15956
• Length: 648
• Species: Homo sapiens
• Alignment Length: 625
• Identity: 118/625 - (18%)
• Similarity: 209/625 - (33%)
• Gaps: 197/625 - (31%)

  Fly    12 PSPTKDYAEGYKPNIPSREPSIQINSSTSNPGSV----RQINKQINVACAVFFLYV------YGG 66
            |.|....|.|....:.:.|.|..:.|:.:..|.|    |...:|........|:||      .||
Human    28 PEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGG 92

  Fly    67 MDFAHSAG------------------WNQTLNTTATQVFKCSWFIGVLAGAALASLTMTFLPKLP 113
            ..|.:..|                  |.:.|.::.         :|..|.:|||.
Human    93 FLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSST---------VGAAAVSALAG---------- 138

  Fly   114 FYVLGGLMQLTGSIIFTCKPFDYG-----------CLLAARYVAGAGIGLITVPFLIHSAEVATD 167
             ..|.|:.....:|:.....|..|           .|||.|.|.|.|||:.::...::.|||:..
Human   139 -GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPP 202

  Fly   168 NHRG---------VSGSMEQCGLALGIAIQVIYDTQWVDDKEASVNEVHGIIGIVFSIIGLGMTA 223
            |.||         ::|......:..| |...:....|        ..:.|:..:...|...|...
Human   203 NLRGRLVTINTLFITGGQFFASVVDG-AFSYLQKDGW--------RYMLGLAAVPAVIQFFGFLF 258

  Fly   224 LSIESPIYYLRIKQKEKARKCHAKLLGSFNHSVDQEFEEIQLYVAESQKR------TFCQEL--- 279
            |. |||.:.::..|.:|||:..:::.|  |.::|:|::.|:..:.|.:|.      ..|:.|
Human   259 LP-ESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYP 320

  Fly   280 --RISVVPFIKLLLYRGFVAFSFSLPLSESLIKSALLTEGFISCWPVTVWGLVRLLGALVAQGFL 342
              |.:::....|.:::.....:..:..|.::::.:.:.:..::.|..:|......:..||....:
Human   321 PTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLV 385

  Fly   343 DKLGRK---FVSLVG-LLCMAILML-------------------------CMAASYAN------- 371
            :|:||:   |.||.| .:.:.||.|                         |...||.|
Human   386 EKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPD 450

  Fly   372 ------------------PANALMT-------------------YYMYQVWRLGLAFQAFAGLFV 399
                              |.|...|                   ::.|.......::.|..||.
Human   451 CGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLI- 514

  Fly   400 CSSSVYL---------------GEAFPIKVK------PFFVGYIIGFEQTIHIINIVGYNKGYEN 443
                :||               .|.:|:..:      ...:.:|.....::..::...|...|..
Human   515 ----LYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGA 575

  Fly   444 FF-YHYYLSVGIILLVGVVFFGIVIPETKKTTLREATKLF 482
            || |..:.:||::.:.|      .:||||...|.|...||
Human   576 FFLYAGFAAVGLLFIYG------CLPETKGKKLEEIESLF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17929	NP_650532.2	MFS	90..477	CDD:475125	95/512 (19%)
SLC2A13	NP_443117.3	MFS_HMIT_like	87..596	CDD:340918	96/551 (17%)