Protein Alignment CG6901 and MPH3

DIOPT Version :10

• Sequence 1: NP_650531.1
• Gene: CG6901 / 41977
• FlyBaseID: FBgn0038414
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_012694.1
• Gene: MPH3 / 853625
• SGDID: S000003921
• Length: 602
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 104/567 - (18%)
• Similarity: 180/567 - (31%)
• Gaps: 200/567 - (35%)

  Fly    19 IATAPPPEPRKPA------VTTNNRGYFTRINKQNYASYTVFFLFIY-----------GGMDMAA 66
            :|||....|:..|      .|....||.|.|....||      |.|:           |..:::|
Yeast    87 LATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYA------LPIFQRKFGSQNDKTGEWEISA 145

  Fly    67 SLGWSQPYSVLLFTEYSYCWFVGVIIGALATTLTMSFLPKLVYYVFGALMQLTG-SIIFTAADYS 130
            |  |.        ...:.|:..|.|:|                      :|||| |:......|:
Yeast   146 S--WQ--------IGLTLCYMAGEIVG----------------------LQLTGPSVDLVGNRYT 178

  Fly   131 ACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGVNGGMEQCGLALGIF--FQVIFTTE------ 187
            ..:|..:||..       .|:::    ..|:|..:..|...||:..|.|  ..|.:.:|
Yeast   179 LIIALFFLAAF-------TFILY----FCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLAL 232

  Fly   188 -----------W---------------TSLIDSN-----PNEIHGIIGIVVSLFGLAMTALVVES 221
                       |               ....||.     |..:..|:.:.::| |:....   ||
Yeast   233 RYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPVPLAL-GIFFAP---ES 293

  Fly   222 PIFFLRRNMENRAQQS----------------------------QEKLLRHNPGGVSAALKE--- 255
            |.:.:::...:.|::|                            :||.|....|..|...::
Yeast   294 PWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKIN 358

  Fly   256 ARR----YVAESDNRTLGEELVASVMPFLKMLLFRCFVAFSFSLPLTMSIISSTAV---AEKGLS 313
            .||    .:..:...|.|..|:.....|.:.......::|:||:......|.:|.:   |.|...
Yeast   359 RRRTRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFG 423

  Fly   314 LWPIYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMAG-LMLGLAGLYANVTNLISFNLMTSA 377
            .:.:|.||:     ....::|....|....|..|..:.:| |::.:|..|
Yeast   424 RYDLYAFGL-----AFQTIVFFIIGGLGCSSTHGSKMGSGSLLMAVAFFY--------------- 468

  Fly   378 CNIALAFQVFAGLFVCSSSAYMGEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSSV--------- 433
             |:.:|..||..:....||.       :|.|:     |::.....::|.|.|...:
Yeast   469 -NLGIAPVVFCLVSEMPSSR-------LRTKT-----IILARNTYNVVSIICSVLILYQLNSKKW 520

  Fly   434 ---PNKDFFFQYFLAVGIIMLVGMIFFTVSMPETKKMTLRKAGHRFQ 477
               ....||:      |::....:|:..|.:|||...|..:....|:
Yeast   521 NWGAKSGFFW------GVLCFCTLIWAVVDLPETAGKTFVEINELFK 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	MFS	66..469	CDD:475125	87/493 (18%)
MPH3	NP_012694.1	SP	72..556	CDD:273317	103/560 (18%)