DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6901 and HXT9

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	549	Identity:	125/549 - (22%)
Similarity:	197/549 - (35%)	Gaps:	167/549 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ATAPPPE-PRKP--AVTT--------------------------NNRGYFTRINKQN----YASY 51
            ||.||.: |:||  |.||                          |...:..|..::|    |...
Yeast    43 ATEPPIDLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLS 107

  Fly    52 TVFFLFIYGGMDMAASLGWSQPYSVLLFTEYSYCWFVGVIIGALATTLTMSFLPKLVYYVFGALM 116
            .|....|....::..::|     .::|..       ||.|.|.....:|::.:     ||.|.|:
Yeast   108 KVRMGLIVSIFNIGCAIG-----GIVLSK-------VGDIYGRRIGLITVTAI-----YVVGILI 155

  Fly   117 QLTGSIIFTAADYSACLAARYLAGLGIGLITV--PFLIHNAEVASNNLRGVNGGMEQCGLALGIF 179
            |:|     :...:......|.::|||:|.|.|  |.||  :|||...:||....:.|....:|||
Yeast   156 QIT-----SINKWYQYFIGRIISGLGVGGIAVLSPMLI--SEVAPKQIRGTLVQLYQLMCTMGIF 213

  Fly   180 FQVIFTTEWTSLIDSNPNEIHGIIGIVV--SLFGLAMTALVVESPIFFLRRNMENRAQQSQEKLL 242
            ..  :.|.:.:....|..:....:|:..  :.|.::....|.|||.:.:....:..|::|   |.
Yeast   214 LG--YCTNYGTKNYHNATQWRVGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRS---LS 273

  Fly   243 RHNPGGV-SAALKEARRYVAESDNRTLGEEL--VASVMPFLKMLLFRCFVAFSFSLPLTMSIISS 304
            :.|...| ..||      :||.|....|.||  :|....:.::|..:..|   |...|...:|.|
Yeast   274 KSNKVSVDDPAL------LAEYDTIKAGIELEKLAGNASWSELLSTKTKV---FQRVLMGVMIQS 329

  Fly   305 ---------------TAVAEKGL--SLWPIYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMA 352
                           |.....||  |.....:.||:......:|:..::..||:...|.|    |
Yeast   330 LQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWG----A 390

  Fly   353 GLMLGLAGLYAN--VTNL----ISFNLMTS--ACNIALAFQVF----------AGLFVCSSSAYM 399
            ..||....::|:  ||.|    .|...:||  |.|..:.|.:|          .|.:|..|
Yeast   391 ASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVS---- 451

  Fly   400 GEAFPMRVKS----------------------FLVGVIVIIEQIVHIVVIACVSSVPNKDFFFQY 442
             |.||:||||                      |:.|.|                     :|::.|
Yeast   452 -ETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAI---------------------NFYYGY 494

  Fly   443 FLAVGIIMLVGMIFFTVSMPETKKMTLRK 471
            .....::.....:||.|  ||||.:||.:
Yeast   495 VFLGCLVFAYFYVFFFV--PETKGLTLEE 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	105/447 (23%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	48/243 (20%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	115/528 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342925
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740