DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6901 and RGT2

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_010143.1	Gene:	RGT2 / 851417	SGDID:	S000002297	Length:	763	Species:	Saccharomyces cerevisiae

Alignment Length:	550	Identity:	118/550 - (21%)
Similarity:	203/550 - (36%)	Gaps:	133/550 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TTVDPVPSPPQETIIIATAPPPEPRKPAVTTNNRGYFTRINKQNYASYTVFFLFIYG-GM----- 62
            |..:|......||..|..: .|.|.:..|.:...|.|..:..         |||.|. |:
Yeast    70 TNNEPAGDGAIETTSILLS-QPLPLRSNVMSVLVGIFVAVGG---------FLFGYDTGLINSIT 124

  Fly    63 DMAASLGWSQPYSVLLFTEYSYCWF-------------VGVIIGALATTL---------TMSFLP 105
            ||        || |..:...::.:|             :|...|||....         |:.|..
Yeast   125 DM--------PY-VKTYIAPNHSYFTTSQIAILVSFLSLGTFFGALIAPYISDSYGRKPTIMFST 180

  Fly   106 KLVYYVFGALMQLTGSIIFTAADYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGVNGGME 170
            .:::.:..:|...:|.::.       .:..|.::|:|||:|:....::.||.|..||||......
Yeast   181 AVIFSIGNSLQVASGGLVL-------LIVGRVISGIGIGIISAVVPLYQAEAAQKNLRGAIISSY 238

  Fly   171 QCGLALGIFFQVIFTTEWTSLIDSNPNEIHGIIGIVV---SLFGLAMTALVVESPIFFLRRNMEN 232
            |..:.:|:......:....|  .:.|:.....||:..   |:..:.|..| .|||.:::.::..|
Yeast   239 QWAITIGLLVSSAVSQGTHS--KNGPSSYRIPIGLQYVWSSILAVGMIFL-PESPRYYVLKDELN 300

  Fly   233 RAQQSQEKLLRHNPGGVSAALKEARRYVAESDNRTLGEELV---------ASVMPFLKMLLFRCF 288
            :|.:|...|                |.:...|.|.| ||||         ||..|   ..|..||
Yeast   301 KAAKSLSFL----------------RGLPIEDPRLL-EELVEIKATYDYEASFGP---STLLDCF 345

  Fly   289 VAFSFSLPLTMSIISSTAV----AEKGLSLWPIYLFGV-------------LRVIGVMVALIF-- 334
            ..........:.|.:..|:    ...|::.  |:.:||             :..|...|.:.|
Yeast   346 KTSENRPKQILRIFTGIAIQAFQQASGINF--IFYYGVNFFNNTGVDNSYLVSFISYAVNVAFSI 408

  Fly   335 -----LDTLGRKAVSLVG--LLVMAGLMLGLAGLYANVTNLISFNLMTSACNIALAFQVFAGLFV 392
                 :|.:||:.|.|.|  ::.:|.|::.:.|:....|.:.|..::...|....||....|..|
Yeast   409 PGMYLVDRIGRRPVLLAGGVIMAIANLVIAIVGVSEGKTVVASKIMIAFICLFIAAFSATWGGVV 473

  Fly   393 CSSSAYMGEAFPMRVKSFLVGVIVIIEQIV---------HIVVIACVSSVPNKDFFFQYFLAVGI 448
            ...||   |.:|:.|:|....:......:|         :||.:...:|......||.:    |.
Yeast   474 WVVSA---ELYPLGVRSKCTAICAAANWLVNFTCALITPYIVDVGSHTSSMGPKIFFIW----GG 531

  Fly   449 IMLVGMIFFTVSMPETKKMTLRKAGHRFQK 478
            :.:|.:|....::.||:.:||.:....|:|
Yeast   532 LNVVAVIVVYFAVYETRGLTLEEIDELFRK 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	94/452 (21%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	48/228 (21%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	114/536 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830