DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6901 and SNF3

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	541	Identity:	107/541 - (19%)
Similarity:	210/541 - (38%)	Gaps:	112/541 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTTTVDPVPSPPQETIIIATAPPPEPRKPAVTTNNRGYFTRINKQNYASYTVFFLFIY--GGMD 63
            |.:...|.:.:....:|:.:..|..:....::..   |.|..:..         |||.|  |.::
Yeast    67 MTSVFTDDISTIDDNSILFSEPPQKQSMMMSICV---GVFVAVGG---------FLFGYDTGLIN 119

  Fly    64 MAASLGW-------------SQPYSVLLFTEYSYCWFVGVIIGALATTLTMSFL-------PKLV 108
            ...|:.:             :|..|:|:    |:. .:|...||    ||..|:       |.::
Yeast   120 SITSMNYVKSHVAPNHDSFTAQQMSILV----SFL-SLGTFFGA----LTAPFISDSYGRKPTII 175

  Fly   109 Y---YVFGALMQLTGSIIFTAADYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGVNGGME 170
            :   ::|    .:..|:...|...:..:..|.::|:|||.|:....::.||....:|||......
Yeast   176 FSTIFIF----SIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTY 236

  Fly   171 QCGLALGIFFQVIFTTEWTSLIDSNPNEIH-GIIGIVVSLFGLAMTALVVESPIFFLRRNMENRA 234
            |..:..|:......:....:..|::...|. |:..:..|...:.|..| .|||.:::.::..:.|
Yeast   237 QWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFLAIGMFFL-PESPRYYVLKDKLDEA 300

  Fly   235 QQSQEKLLRHNPGGVSAALKEARRYVAESD-NRTLGEE-----LVAS---------VMPFLKMLL 284
            .:|. ..||..|...|..|:|.....|..| ..:.|..     .::|         :...:.:..
Yeast   301 AKSL-SFLRGVPVHDSGLLEELVEIKATYDYEASFGSSNFIDCFISSKSRPKQTLRMFTGIALQA 364

  Fly   285 FRCFVAFSFSLPLTMSIISSTAVAEKGLSLWPIYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLL 349
            |:.|...:|.....::..:.|.|:...|..:..|   .:.|:..:..|.|::..||:.|     |
Yeast   365 FQQFSGINFIFYYGVNFFNKTGVSNSYLVSFITY---AVNVVFNVPGLFFVEFFGRRKV-----L 421

  Fly   350 VMAGLMLGLAGLYANVTNLISFNLMT-SACNIALAFQVFAGLFVCSSSAYMG--------EAFPM 405
            |:.|:::.:|..   :..::..:|.| :|..:.:|   |..||:.:.||..|        |.:|:
Yeast   422 VVGGVIMTIANF---IVAIVGCSLKTVAAAKVMIA---FICLFIAAFSATWGGVVWVISAELYPL 480

  Fly   406 RVKSFLVGVIVIIEQIVHIVVIAC-------------VSSVPNKDFFFQYFLAVGIIMLVGMIFF 457
            .|:|....:......:|:.:   |             .||:..|.||..     |.:..:|:|..
Yeast   481 GVRSKCTAICAAANWLVNFI---CALITPYIVDTGSHTSSLGAKIFFIW-----GSLNAMGVIVV 537

  Fly   458 TVSMPETKKMTLRKAGHRFQK 478
            .:::.|||.:||.:....:.|
Yeast   538 YLTVYETKGLTLEEIDELYIK 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	88/431 (20%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	42/215 (20%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	102/505 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830