DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6901 and GEX1

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_009863.2	Gene:	GEX1 / 850289	SGDID:	S000000575	Length:	615	Species:	Saccharomyces cerevisiae

Alignment Length:	540	Identity:	116/540 - (21%)
Similarity:	196/540 - (36%)	Gaps:	142/540 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RGYFTRINKQNYASYTVFFLFIYGGMDMAASLGWSQPYSVL--------LFTEYSYCWFVGVIIG 93
            |..:|.....:|:.:::  |.....::...|:|....||.|        ||...:..:.:|.||.
Yeast    80 RSTYTGYATNSYSEHSL--LSTVQVINAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQ 142

  Fly    94 ALATTLTMSFLPKLVY---YVFGALMQLTGSIIFTAADYSACLAAR--YLAGLGIGLITVPFLIH 153
            :.||.|||.....:.|   || |..:.||    ...:|:|: |..|  |........|.:|::..
Yeast   143 SQATRLTMYAAGSVFYNCGYV-GTNLLLT----LILSDFSS-LKWRMFYQYASYWPYIIIPWISG 201

  Fly   154 NAEVASNNLRGVNGGMEQCGL-----ALGIFFQVIF-------TTEWTSLIDSNPNE-------- 198
            |...|:|..:..:..:.....     ||.|.|.:::       |.||.||.:....|
Yeast   202 NIITAANPQKNWSWNIAMWAFIYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFEN 266

  Fly   199 ---------IHGIIGIVVSL------FGLA------------MTALVVESPIFFLRRNMENRAQQ 236
                     |.||:.|.|||      ..||            :..||....:||:....|.:..:
Yeast   267 LVFLFWKLDIVGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAK 331

  Fly   237 S---QEKLLRHN----PGGVS-------------------AALKEARRYVAESDNRTLGEELVAS 275
            |   ..|||...    |.||:                   .::||:....|...|  |.:.:.|:
Yeast   332 SPLLPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVN--LPDFVAAT 394

  Fly   276 VMPFLKMLLFRCFVAFSFSLPLTMSIISSTAVAEKGLSLWPIYLFGVLRVIGVMVAL-IFLDTLG 339
            ..||..:|:.:       :..|.:|:|.       |.:.|             ||.: :|....|
Yeast   395 ASPFYSLLVAK-------TRKLKLSVIG-------GCAAW-------------MVCMGLFYKYRG 432

  Fly   340 RKAVSLVGLLVMAGLMLGLAGLYANVTNLISFNLMTSACNIALAFQV---FAGLFVCSSSAYMGE 401
            ... |..| ::.|.:::||:||..:.:.::....||:...:|:...:   |:.|.....::..|.
Yeast   433 GSG-SHEG-VIAASVIMGLSGLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGA 495

  Fly   402 AFPMRVKSFL---VGVIVIIEQIVHIVVIACVSSV----PNKDFFFQ-YFLAVGIIMLVGMI--- 455
            .:...:.:.|   :|...:.| |.:......:|..    |.:|...: |.....|||.||:.
Yeast   496 IWTQTMPNQLYKNLGNDTLAE-IAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTV 559

  Fly   456 -FFTVSMPETKKMTLRKAGH 474
             ||..:|.......:.||.|
Yeast   560 PFFAFTMFMRDPELIDKATH 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	102/477 (21%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	39/200 (20%)
GEX1	NP_009863.2	MFS_ARN_like	59..571	CDD:340880	113/530 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900