Protein Alignment CG6901 and SLC2A3

DIOPT Version :9

• Sequence 1: NP_650531.1
• Gene: CG6901 / 41977
• FlyBaseID: FBgn0038414
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 107/468 - (22%)
• Similarity: 172/468 - (36%)
• Gaps: 110/468 - (23%)

  Fly    69 GWSQPYSVLLFTEYSY---CWFVGVIIGALATTLTMSFLPKLVYYVFGALMQLTGSIIF----TA 126
            |.:.|..|||.:.:|.   .:.||.:||:.:..|.::...:....:...|:.:||....    .|
Human    50 GNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVA 114

  Fly   127 ADYSACLAARYLAGLGIGLIT--VPFLIHNAEVASNNLRGVNGGMEQCGLALGIFFQVIFTTE-- 187
            ......:..|.:.||..||.|  ||..|  .|::...|||..|.:.|.|:.:||....||..|
Human   115 KSVEMLILGRLVIGLFCGLCTGFVPMYI--GEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFI 177

  Fly   188 ------WTSLIDSNPNEIHGIIGIVVSLFGLAMTALVVESPIFFL-RRNMENRAQQSQEKLLRHN 245
                  |..|:.         ..|:.::...|......|||.|.| .|..|..|:|..::|  ..
Human   178 LGSEELWPLLLG---------FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRL--WG 231

  Fly   246 PGGVSAALKEARRYVAESDNRTLGEELVASVMPFLKMLLFRCFVAFSFSLPLTMSIISSTAVAEK 310
            ...||..::|.:     .::..:.:|...:|:...::..:|..:..|..|.|:..:....||...
Human   232 TQDVSQDIQEMK-----DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYY 291

  Fly   311 GLSLW-------PIYL---FGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYANV 365
            ...::       |||.   .||:..|..:|:|..::..||:.:.::||..||     .......|
Human   292 STGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMA-----FCSTLMTV 351

  Fly   366 TNLI--SFNLMTSAC-NIALAFQVF-------------AGLFV------------CS---SSAYM 399
            :.|:  ::|.|:..| ...|.|..|             |.||.            ||   |:..:
Human   352 SLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLV 416

  Fly   400 GEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSSVPNKDFFFQYFLAVGIIMLVGMIFFTVSMPET 464
            |..||.  .:..:|..|.|                    .|..||    |..:...||.|  |||
Human   417 GLLFPS--AAHYLGAYVFI--------------------IFTGFL----ITFLAFTFFKV--PET 453

  Fly   465 KKMTLRKAGHRFQ 477
            :..|.......|:
Human   454 RGRTFEDITRAFE 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	99/439 (23%)
		MFS	<272..457	CDD:119392	45/225 (20%)
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	105/456 (23%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		0/5 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840