Protein Alignment CG6901 and SLC2A2

DIOPT Version :9

• Sequence 1: NP_650531.1
• Gene: CG6901 / 41977
• FlyBaseID: FBgn0038414
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 105/511 - (20%)
• Similarity: 196/511 - (38%)
• Gaps: 109/511 - (21%)

  Fly     5 TVDPVPSPPQETIIIATAPPPEPRKPAVTTNNRGYFTRINKQNYASYTVFFLFIYGGMDMAASLG 69
            :.|.:|     ||..:..|.|.|.....|.......|.:...:.:|:.|      |||..:...|
Human    63 STDELP-----TISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAV------GGMTASFFGG 116

  Fly    70 WSQPYSVLLFTEYSYCWFVGVIIGALATTLTMSFLPKLVYYVFGALMQLTGSIIFTAADYSACLA 134
            |                 :|..:|.:...|..:.|.     :.|||:.....:   ...:...:|
Human   117 W-----------------LGDTLGRIKAMLVANILS-----LVGALLMGFSKL---GPSHILIIA 156

  Fly   135 ARYLAGLGIGLIT--VPFLIHNAEVASNNLRGVNGGMEQCGLALGIFFQVIFTTE--------WT 189
            .|.::||..|||:  ||..|  .|:|...|||..|...|..:..||....|...|        |.
Human   157 GRSISGLYCGLISGLVPMYI--GEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWH 219

  Fly   190 SLIDSNPNEIHGIIGIVVSLFGLAMTALVVESPIF-FLRRNMENRAQQSQEKLLRHNPGGVSAAL 253
            .|:.     :.|:..|:.||    :.....|||.: :::.:.|.:|:||.::|..::  .|:..:
Human   220 ILLG-----LSGVRAILQSL----LLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYD--DVTKDI 273

  Fly   254 KEARRYVAESDNRTLGEELVASVMPFLKMLLFRCFVAFSFSLPLTMSII---------------- 302
            .|.|:...|:.:..             |:.:.:.|...|:..|:.::::
Human   274 NEMRKEREEASSEQ-------------KVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYY 325

  Fly   303 SSTAVAEKGLSLWPIYL---FGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYAN 364
            |::.....|:|. |:|.   .|.:.::...|::..::..||:::.|:|   |:|:.:....:...
Human   326 STSIFQTAGISK-PVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIG---MSGMFVCAIFMSVG 386

  Fly   365 VTNLISFNLMTSACNIALAFQVFAGLFVCSSSA----YMGEAFPMRVKSFLVGVIVIIEQIVHIV 425
            :..|..|:.|:....||:.  :|...|......    .:.|.|....:...:.:........:.:
Human   387 LVLLNKFSWMSYVSMIAIF--LFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFI 449

  Fly   426 VIACVSSVPNKDFF--FQYFLAVGIIMLVGMI-FFTVSMPETKKMTLRKAGHRFQK 478
            |..|...:  .||.  :.:||..|:::...:. ||.|  ||||..:..:....|||
Human   450 VALCFQYI--ADFCGPYVFFLFAGVLLAFTLFTFFKV--PETKGKSFEEIAAEFQK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	86/420 (20%)
		MFS	<272..457	CDD:119392	33/210 (16%)
SLC2A2	NP_000331.1	Sugar_tr	14..499	CDD:278511	102/507 (20%)
		MFS	98..485	CDD:119392	89/453 (20%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	314..320		0/5 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840