DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6901 and slc2a13b

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_005163236.1	Gene:	slc2a13b / 559440	ZFINID:	ZDB-GENE-090812-1	Length:	641	Species:	Danio rerio

Alignment Length:	542	Identity:	99/542 - (18%)
Similarity:	190/542 - (35%)	Gaps:	128/542 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 YTVFFLFIYGGMDMAASLGWSQPYSVLLFTE--YSYCW---FVGVIIGALA-TTLTMSFL----P 105
            ||:.|....||.......|......:||..|  .|..|   .|.:.:||.| :.|...||    .
Zfish    36 YTLAFFSALGGFLFGYDTGVVSGAMLLLKREKKLSSVWQELLVSITVGAAAVSALAGGFLNGRFG 100

  Fly   106 KLVYYVFGALMQLTGSIIFTAA-DYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRG----- 164
            :.|..:..:.:...|.||.:.| :..|.|..|...|||:|:.::...::.|||:..:|||
Zfish   101 RRVCILLASFIFCAGGIILSVARNKEALLCGRLTVGLGLGIASMTVPVYIAEVSPPDLRGQLVTV 165

  Fly   165 ----VNGGMEQCGLALGIFFQVIFTTEWTSLIDSNPNEIHGIIGIVVSLFGLAMTALVVESPIFF 225
                :.||.....:..|. |..:....|..::..:      ::...:...|.   ..:.|||.:.
Zfish   166 NTLFITGGQFIASVVDGA-FSYLPHDGWRFMLGLS------VVPAALQFLGF---LFLPESPRWL 220

  Fly   226 LRRNMENRAQQSQEKLLRHNPGGVSA--ALKEARRYVAESDNRTLGEELVASVM---PFLKMLLF 285
            |::..    .|:...:||...|.|..  ..:..|..:.|......|..::..::   |..:.|:.
Zfish   221 LQKGF----TQNALLVLRQIRGDVDVEEEFESIRCSIQEEQRDVAGGPVLWRMLASPPARRALIV 281

  Fly   286 RC-------FVAFSFSLPLTMSIISSTAVAEKGLSLWPIYLFGVLRVIGVMVALIFLDTLGRKAV 343
            .|       ....:..:..:.:|:..:.|.:..:::|..........:..:|.:..::.:||:.:
Zfish   282 GCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVGRRRL 346

  Fly   344 SLVGLLVMA-GLMLGLAG--LYANVTNLISF-----NLMTSAC-------------NIALAFQVF 387
            ::..||..| .||:..||  |.|..:..::|     ::..|.|             :....:.:.
Zfish   347 TMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNYGFCESCMLDPDCGFCYGLN 411

  Fly   388 AGLFVCSS----------SAYMGEAFPMRVKS-----------------FLVGVIVI-------- 417
            |...|.||          :|.:|..|....|:                 .|:|:|:.
Zfish   412 ATAVVQSSCVPVDPANTETAALGRCFNGTQKASSVFWAYNYCPTPYSWVVLLGLILYLAFFAPGM 476

  Fly   418 --------------------------IEQIVHIVVIACVSSVPNKDFFFQYFLAVGIIMLVGMIF 456
                                      :..|.:::|......|.....::..|.....:.|:|.:|
Zfish   477 GPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALLGFVF 541

  Fly   457 FTVSMPETKKMTLRKAGHRFQK 478
            .:..:||||.:.|.:....|.:
Zfish   542 VSGCLPETKGLRLEEIESLFSR 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	87/495 (18%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	38/276 (14%)
slc2a13b	XP_005163236.1	Sugar_tr	38..561	CDD:278511	96/536 (18%)
slc2a13b	XP_005163236.1	MFS	40..542	CDD:119392	90/515 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840