DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6901 and CG17930

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_650533.1	Gene:	CG17930 / 41979	FlyBaseID:	FBgn0038416	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	237/508 - (46%)
Similarity:	333/508 - (65%)	Gaps:	29/508 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTTTVDPVPSPPQETIIIATAP-------------PPEPRKPA----VTTNNRGYFTRINKQNY 48
            |.||.|...|.|.|:|..|.|.|             ||.|..|.    .|.:|..:.|....|:.
  Fly     1 MTTTYVTAGPVPVQQTTYITTGPQQTTYITNGRQQQPPPPPPPTTVIITTQSNSRWATPTQTQSG 65

  Fly    49 ASYTVFFLFIYGGMDMAASLGWSQPYSVLLFTEYSYCWFVGVIIGALATTLTMSFLPKLVYYVFG 113
            .:.|:  ||:|.|||||..|||:.........|:.|.||:||||||:.:.:|.:||||:|:|..|
  Fly    66 TAATL--LFVYAGMDMAQGLGWNLTAVSANTLEFQYSWFIGVIIGAVVSAITSAFLPKIVFYGLG 128

  Fly   114 ALMQLTGSIIFTAA--DYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGVNGGMEQCGLAL 176
            .:|.|..:|||.:|  :|.:.|||||:.|:||||||||||||:||:||:..||....:||.||||
  Fly   129 GVMNLIDAIIFVSAPYEYESILAARYVGGVGIGLITVPFLIHSAEIASSTNRGTCCALEQYGLAL 193

  Fly   177 GIFFQVIFTTEWTSLIDSNPNEIHGIIGIVVSLFGLAMTALVVESPIFFLRRNMENRAQQSQEKL 241
            |:..|||:.::|:..:....|.:|||.|||.:...|...|:.::||||::|:|.|.:|:.|.::|
  Fly   194 GVAIQVIYDSQWSQGLGMTINRVHGIFGIVFTAIALGSVAITIDSPIFYIRQNQEQKARASVKQL 258

  Fly   242 L----RHNPGGVSAALKEARRYVAESDNRTLGEELVASVMPFLKMLLFRCFVAFSFSLPLTMSII 302
            :    ....|  ..|..||:.||.|...:.:||:|..|:|||||:|||||||||:||:||:.||:
  Fly   259 MGSYWTREAG--DRAYDEAKLYVVEGSAQGVGEQLGESMMPFLKLLLFRCFVAFTFSVPLSYSIL 321

  Fly   303 SSTAVAEKGLSLWPIYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYANVTN 367
            ::|.:.|..|..||..:||:||:||.::....|||:|||.|||:||:.|||||||:||:|.:..:
  Fly   322 TTTELVEGTLHSWPTIIFGLLRLIGALITFAVLDTVGRKFVSLLGLMCMAGLMLGMAGVYGDYGH 386

  Fly   368 LISFNLMTSACNIALAFQVFAGLFVCSSSAYMGEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSS 432
            :.....|...|.:.:|||.|||.|:||||||:|||||||||.||:|:||.:||::||:||  |..
  Fly   387 IFDDYFMWQVCRLGMAFQFFAGFFICSSSAYLGEAFPMRVKPFLIGLIVCLEQVIHIIVI--VKF 449

  Fly   433 VPNKDFFFQYFLAVGIIMLVGMIFFTVSMPETKKMTLRKAGHRFQKWYDVQMY 485
            ||..:|::.||:||||||::|::.|.|.||||:.:|||:||.||::.:||..|
  Fly   450 VPTAEFYYTYFVAVGIIMVIGLVAFAVLMPETRGLTLRQAGERFRRVHDVMAY 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	194/389 (50%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	102/184 (55%)
CG17930	NP_650533.1	Sugar_tr	102..493	CDD:278511	198/394 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471777
Domainoid	1	1.000	93	1.000	Domainoid score	I13956
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I7306
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26811
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005925
OrthoInspector	1	1.000	-	-		mtm9616
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900