DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6901 and CG42825

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_729590.1	Gene:	CG42825 / 39179	FlyBaseID:	FBgn0262007	Length:	518	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	143/502 - (28%)
Similarity:	239/502 - (47%)	Gaps:	49/502 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PVPSPPQETIIIAT----APPPEPRKPAVTTN-NRGYFTRINK---QNYASYTVFFLFIYGGMDM 64
            |.|..||......|    .||..||.|....: ..|.|.|..|   |:.|......:||.|||::
  Fly    31 PQPGQPQHITPAETYGPQPPPMPPRDPHTRVDPPGGCFQRNQKNKPQSNAVGAAGLIFISGGMNI 95

  Fly    65 AASLGWSQP--YSVLLFTEYSY-CWFVGVIIGALATTLTMSFLPKLVYYVFGALMQLTGSIIF-- 124
            |.::|:..|  |..   |:::| .||:|.|||||.|....:.:.|.....|.:::...|.::.
  Fly    96 AWAIGFQGPIYYQT---TKHNYIAWFIGAIIGALVTMALTNKVAKKYILQFSSVLVTVGGLVIAC 157

  Fly   125 TAADYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRG-VNGGMEQCGLALGIFFQVIFTTEW 188
            |..:.:...||.||.|:..||:..||:....|::...||| .:..:||.....||..|:::.:.|
  Fly   158 THNNGAGTTAACYLDGIANGLVFAPFMALVGEISVPYLRGKASATLEQLCFGTGILLQILYVSNW 222

  Fly   189 T-----SLIDSNPNEIHGIIGIVVSLFGLAM-TALVVESPIFFLRRNMENRAQQSQEKLLRHNPG 247
            |     :..|.....:.|::..:..:..|.| :...:|||:..|..|.|..|..:..:|  ..|.
  Fly   223 TYSSYMTYNDFTSENMKGVLSTIYGVLALIMGSFFTIESPVLMLANNEEQAAIDALRRL--QKPA 285

  Fly   248 GVS----AALKEARRYVAESDNRTLGEELVASVMPFLKMLLFRCFVAFSFSLPLTMSIISSTAVA 308
            .::    ..|.|.:||:|.:.|.:..|.:..::..|:::...|...|.|.|..:.::.:.:..|:
  Fly   286 VLTEETYELLAEHKRYLAYNKNMSKSESISKALPTFMRLAYLRALNAMSISSFVIITYVVAILVS 350

  Fly   309 E--KGLSLWPIYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYANVTNLISF 371
            .  :..|.|.|.| ...|.:|.::....:::||||..::.||||..||...:...| ||     :
  Fly   351 NDLRNASSWYIGL-AFCRWLGSLIPSFCMESLGRKKPAVFGLLVSCGLSFAVGSQY-NV-----Y 408

  Fly   372 NLMTSACNIALAFQVFAGLFVCSSSAYMGEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSSVPNK 436
            ..|:....:.:.|:.|||:...|:|||:.||:||.||...:|:..|.|..|.:::..|
  Fly   409 TYMSQVTVLIMIFEFFAGMAFSSNSAYLTEAYPMGVKQHFIGLTFITEIFVFLIINVC------- 466

  Fly   437 DFFF----QYFLAVGIIMLVGMIFFTVSMPETKKMTLRKAGHRFQKW 479
            ||.|    .||..:|.:.|.|:|...:::|||::|||:.|..:|.|:
  Fly   467 DFNFGQGYNYFYIMGAMYLAGVILGVLTLPETRRMTLQGAQEQFNKF 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	111/402 (28%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	54/190 (28%)
CG42825	NP_729590.1	MFS	116..490	CDD:119392	106/389 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444571
Domainoid	1	1.000	93	1.000	Domainoid score	I13956
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I7306
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26811
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005925
OrthoInspector	1	1.000	-	-		mtm9616
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900