DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6901 and ght3

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_592790.1	Gene:	ght3 / 2541758	PomBaseID:	SPAC1F8.01	Length:	555	Species:	Schizosaccharomyces pombe

Alignment Length:	476	Identity:	107/476 - (22%)
Similarity:	181/476 - (38%)	Gaps:	110/476 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 NKQNYASYTVFFL--FIYGGMDMAASLGWSQPYSVLLFTEYSYCWFVGVIIGALATTLTMSFLPK 106
            |..:|:::....|  .|..|....|.|  |.|::..:..:||.|:|.||.|  :|..|.::.:|.
pombe    49 NSYSYSAWRQALLTGTINAGCLFGAML--SSPFTERIGKKYSICFFSGVYI--IAELLLVTAVPS 109

  Fly   107 LVYYVFGALMQLTGSIIFTAADYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGVNGGMEQ 171
            .:..:.|                      :.|||:|||.::|....:.:|||...:||
pombe   110 WIQVLVG----------------------KILAGVGIGALSVLSPGYQSEVAPPQIRG------- 145

  Fly   172 CGLALGIFFQVIF-------------------TTEW-TSLIDSNPNEIHGIIGIVVSLFGLAMTA 216
               |:...:|:..                   |..| ||.   ..|.:.||:.:|..||
pombe   146 ---AVVATYQIFSTGAALVAACINMGTHKLRKTASWRTSF---GINMLWGILLMVGVLF------ 198

  Fly   217 LVVESPIFFL--------RRNMENRAQQSQE-KLLRHNPGGVSAALK-----EARRYVAESDNRT 267
             :.|||.:.:        .|.|.|.|:.|.| ::::.|...:.:.::     ...|::     ..
pombe   199 -LPESPRYLIYKGRDEEALRIMCNMAELSPESEIIQTNFNTIKSDIEIEMAGGKARWI-----EI 257

  Fly   268 LGEEL-VASVMPFLKMLLFRCFVAFSFSLPLTMSIISSTAVAEKGLSLWPIYLFGVLRVIGVMVA 331
            .|::: ..:.:.|| ::|||..:..::.......:...|.:.:..|   |..:.|.:.......|
pombe   258 FGKDIRYRTCLGFL-VMLFRELIGNNYYFYYATQVFKGTGMTDIFL---PAVILGAINFGTTFGA 318

  Fly   332 LIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYANV--TNLISFNLMTSACNIALAFQVFAGLFV-- 392
            |..:|.|||:...:.|....:....    :||.|  ..||..| .||.........||:.||:
pombe   319 LYTIDNLGRRNPLIFGAAFQSICFF----IYAAVGDRKLIYKN-GTSDHRAGSVMIVFSCLFLFS 378

  Fly   393 -CSSSAYM-----GEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSSVPNK-DFFFQYFLAVGIIM 450
             |.|...|     ||.||:|.:|....|......:.:.::......:.|. .|...|..|...:.
pombe   379 YCCSWGPMGWVIVGETFPIRYRSKCASVATSGNWLGNFMISFFTPFINNAIGFKLGYIYACINLF 443

  Fly   451 LVGMIFFTVSMPETKKMTLRK 471
            ...||||...  |||.:||.:
pombe   444 SSFMIFFLAK--ETKGLTLEE 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	94/429 (22%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	44/196 (22%)
ght3	NP_592790.1	Sugar_tr	9..467	CDD:278511	107/476 (22%)
ght3	NP_592790.1	MFS	10..452	CDD:119392	102/462 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810