DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6901 and ght4

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_595064.1	Gene:	ght4 / 2539710	PomBaseID:	SPBC1683.08	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	492	Identity:	103/492 - (20%)
Similarity:	181/492 - (36%)	Gaps:	111/492 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 NKQNYASY-------TVFFLFIYGGMDMAASLGWSQPYSVLLFTEYSYCWFVG-VIIGALATTLT 100
            |..:|:::       ||....::|.|       .|.|::..:..:||..:|.| .|||.:   |.
pombe    49 NSYSYSAWRQALLTGTVNAGCLFGAM-------LSSPFTEAIGKKYSIAFFSGCYIIGQI---LL 103

  Fly   101 MSFLPKLVYYVFGALMQLTGSIIFTAADYSACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGV 165
            ::.:|..|..:.|.|        ||              ||.||.::|....:.:|||...:||.
pombe   104 VTAVPSWVQIMVGKL--------FT--------------GLTIGALSVLSPGYQSEVAPPQIRGA 146

  Fly   166 NGGMEQ----CGLALGIFF-----QVIFTTEWTSLIDSNPNEIHGIIGIVVSLFGLAMTALVVES 221
            .....|    ||..:....     ::..|..|.:...         |.|:..:|.:.....:.||
pombe   147 VVSTYQLFQTCGTLIAACINMGTHKLRKTASWRTSFG---------INILWGIFLMVGVLFLPES 202

  Fly   222 PIFFLRRNMENRAQQ---------SQEKLLRHNPGGVSAALKEARRYVAESDNRTLGEEL-VASV 276
            |.:.:.:..:..|.:         .:.::::.|...:.:.::..............|:|: ..:|
pombe   203 PRYLIYKGRDEEALRIMCQTAELDPESEIIQTNFNTIKSDIEMEMAGGKARWPEVFGKEVRYRTV 267

  Fly   277 MPFLKMLLFRCFVAFSFSLPLTMSIISSTAVAEKGLSLWPIYLFGVLRVIGVMVALIFLDTLGRK 341
            :.||.||| |..:..::.......:...|.:.:..|   |..:.|.:.......||..:|.|||:
pombe   268 LGFLTMLL-RELIGNNYYFYYATQVFKGTGMTDIFL---PAVILGAINFGTTFGALYTIDNLGRR 328

  Fly   342 AVSLVGLLVMAGLMLGLAGLYANV--TNLISFNLMTSACNIALAFQVFAGLFV---CSSSAYM-- 399
            ...:.|....:....    :||.|  ..||..| .||.........||:.||:   |.|...|
pombe   329 NPLIFGAAFQSICFF----IYAAVGDRKLIYKN-GTSDHRAGAVMIVFSCLFLFSYCCSWGPMGW 388

  Fly   400 ---GEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSSVPNKDFFFQYFLAVGIIMLVGMIFFTVSM 461
               ||.||:|.:|....|......:.:.:|           .||..|::..|...:|.|:..::|
pombe   389 VIVGETFPIRYRSKCAAVATSGNWLGNFMV-----------SFFTPFISNSIGFKLGYIYACINM 442

  Fly   462 ----------PETKKMTLRKAGHRFQ---KWYDVQMY 485
                      .|||.:||.:....::   |.:|...|
pombe   443 TSAFQIFLMAKETKGLTLEEVNELYESDIKPWDSYKY 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	88/423 (21%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	47/195 (24%)
ght4	NP_595064.1	Sugar_tr	9..467	CDD:278511	100/478 (21%)
ght4	NP_595064.1	MFS	10..440	CDD:119392	94/451 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810