DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6901 and Slc2a13

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001028805.2	Gene:	Slc2a13 / 239606	MGIID:	2146030	Length:	637	Species:	Mus musculus

Alignment Length:	500	Identity:	92/500 - (18%)
Similarity:	171/500 - (34%)	Gaps:	151/500 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GVIIGALATTLTMSFLPKLVYYVFGALMQLTGSIIFTAADYSACLAARYLAGLGIGLITVPFLIH 153
            |.:.|||..        :....:..||..:..:::..||:....||.|.:.|||||:.::...::
Mouse   128 GALNGALGR--------RSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVY 184

  Fly   154 NAEVASNNLRG---------VNGGMEQCGLALGIFFQVIFTTEWTSLIDSNPNEIHGIIGI--VV 207
            .|||:..||||         :.||.         ||..:....::.|.......:.|:..|  |:
Mouse   185 IAEVSPPNLRGRLVTINTLFITGGQ---------FFASVVDGAFSYLQKDGWRYMLGLAAIPAVI 240

  Fly   208 SLFGLAMTALVVESPIFFLRRNMENRAQQSQEKLLRHNPGG--VSAALKEARRYVAESDNR-TLG 269
            ...|.   ..:.|||.:.:::....:|:    ::|....|.  :.......|..:.|.:.. |..
Mouse   241 QFLGF---LFLPESPRWLIQKGQTQKAR----RILSQMRGNQTIDEEYDSIRNSIEEEEKEATAA 298

  Fly   270 EELVASVM---PFLKMLLFRCFVAFSFSLP-------LTMSIISSTAVAEKGLSLWPIYLFGVLR 324
            ..::..::   |..:.|:..|.:.....|.       .:.:|:..:.|.:..|::|...:.....
Mouse   299 GPIICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTN 363

  Fly   325 VIGVMVALIFLDTLGRK-------AVSLVGLLVMAGLMLGLAGLYANVTNLISFNLMT------- 375
            .|..:|.:..::.:||:       |.:.|.|:::|   ||.. |.|.|:..::|...|
Mouse   364 FIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILA---LGFL-LSAQVSPRVTFRPTTPSDQNTT 424

  Fly   376 ----SACN-------IALAFQVFAGLFVCSSS-----------------------------AY-- 398
                |.||       ....:::.....:.||.                             ||
Mouse   425 CTGYSYCNECMLDPDCGFCYKINGSAVIDSSCVPVNKASTTEAAWGRCDNETKFKAEGAHWAYSF 489

  Fly   399 -----------------------MG--------EAFPMRVKS----FLVGVIVIIEQIVHIVVIA 428
                                   ||        |.:|:..:|    ...|:..|...:|.:..:.
Mouse   490 CPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLH 554

  Fly   429 CVSSVPNKDFFFQY--FLAVGIIMLVGMIFFTVSMPETKKMTLRK 471
            ....:.....||.|  |.|||::.:.|      .:||||...|.:
Mouse   555 TAEYLTYYGAFFLYAGFAAVGLLFVYG------CLPETKGKKLEE 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	91/496 (18%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	46/287 (16%)
Slc2a13	NP_001028805.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	15..38
		MFS	75..580	CDD:119392	86/479 (18%)
		Sugar_tr	78..598	CDD:278511	92/499 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740