DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6901 and CG42826

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001189079.1	Gene:	CG42826 / 10178905	FlyBaseID:	FBgn0262008	Length:	473	Species:	Drosophila melanogaster

Alignment Length:	498	Identity:	149/498 - (29%)
Similarity:	239/498 - (47%)	Gaps:	74/498 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PPPEPRKPAVTTNNRGYFTRINKQNYASYTVF----FLFIYGGMDMAASLGWSQPYSV------- 76
            ||||   .::.|..:..|.|:..:|::.:|..    |:.|.|||    ||.|...::|
  Fly     8 PPPE---DSLATTEKATFLRLGHKNHSQWTALGSASFILISGGM----SLAWGAGFAVHSAHRDQ 65

  Fly    77 LLFTEY-SYCWFVGVIIGALATTLTMSFLPKLVYYVFGALMQLTGSIIFTAADYSAC----LAAR 136
            ||.|.: ...|:...::|||........||:...|:|.:::.:...|:|.|  :..|    :|||
  Fly    66 LLRTVHMQIAWYATAVLGALFGAFYTHRLPQQPIYIFSSILVIASGILFLA--WPECPGAIIAAR 128

  Fly   137 YLAGLGIGLITVPFLIHNAEVASNNLRGVNGG-MEQCGLALGIFFQVIFTTEWTSLIDSN----P 196
            ||.||..||:.||.|....|::.|.:||:... :||.....||..|:|:|..|.  :|.|    .
  Fly   129 YLDGLANGLVFVPALSTVGEISVNEIRGLLASTVEQLSFNTGILLQLIYTAVWQ--VDWNVAIVA 191

  Fly   197 NEIHGIIGIVVSLFGLAMT-ALVVESPIFFLRRNMENRA-----------QQSQEKLLRHNPGGV 249
            :::||::.||..:..||:. .|.||||:..|.|:.|.||           ..:.|.|||
  Fly   192 DQVHGVLSIVYGVIALALALTLCVESPVHLLMRSSEQRALVALRHLQRPYMVTSEMLLR------ 250

  Fly   250 SAALKEARRYVAESDNRTLGEELVASVMPFLKMLLFRCFVAFSFSLPLTMSIISSTAVAEKG--- 311
               |.|.::|||::....||..|.......||:|..|.....|.:     |||.| |:.|.|
  Fly   251 ---LDEHKQYVADNREMCLGSSLQKGYPSVLKLLALRLLGVLSLN-----SIICS-ALYETGNQL 306

  Fly   312 ---LSLWPIYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYANVTNLISFNL 373
               |..||..:||:||..|...|::.:||.|||..:|.|:.......:..|.|:....::|
  Fly   307 VSCLYAWPFVVFGLLRWGGCFFAVLLMDTTGRKKPTLFGIFSTGAFAIAYANLFGRTPHMI---- 367

  Fly   374 MTSACNIALAFQVFAGLFVCSSSAYMGEAFPMRVKSFLVGVIVIIEQIVHIVVIACVSSVPNKDF 438
              :|..:..:.|.|.||..|:|:.|:.|.||:.:|..:|.|:.|:||...:::.:.:.|:..
  Fly   368 --TALVMLFSLQFFEGLGQCASAVYLTEGFPLLMKPHMVAVVYIMEQAARLLLCSFLPSIAE--- 427

  Fly   439 FFQYFLAVGIIMLVGMIFFTVSMPETKKMTLRKAGHRFQKWYD 481
            ...||.::|.:.:|..:.....:|||:.:||.:|..:|.||::
  Fly   428 ITAYFHSMGALSMVCFLLGIFCLPETRLVTLAEAQLKFSKWFN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	122/410 (30%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	54/190 (28%)
CG42826	NP_001189079.1	Sugar_tr	80..465	CDD:278511	124/412 (30%)
CG42826	NP_001189079.1	MFS	310..>459	CDD:119392	45/157 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444566
Domainoid	1	1.000	93	1.000	Domainoid score	I13956
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I7306
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26811
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005925
OrthoInspector	1	1.000	-	-		mtm9616
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23529
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900