DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6901 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_038967504.1	Gene:	Slc2a7 / 100362644	RGDID:	1583902	Length:	525	Species:	Rattus norvegicus

Alignment Length:	567	Identity:	110/567 - (19%)
Similarity:	204/567 - (35%)	Gaps:	157/567 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TVDPVPSPPQE-----TIIIATAPPPEPRKPAVTTNNRGYFTRINKQNYASYTVFFLFIYG---- 60
            |..|:|||..|     |:::.|..                         |::...|.:.|.
  Rat     6 TGTPLPSPHMEARLQPTLVLTTLS-------------------------AAFGSAFQYGYNIAVI 45

  Fly    61 --GMDMAASLGWSQPYSVLLFTEYSYCWF------------------------VGVIIGALATTL 99
              ...:..|.||...:.||. :.|:..:|                        :|.::|:|...:
  Rat    46 NTPHKVGTSSGWGPVFQVLK-SFYNDTYFERHGTFMDENTLLLLWSCTVSMFPLGGLLGSLVVGM 109

  Fly   100 TMSFLPKLVYYVFGALMQLTGSIIFTAAD----YSACLAARYLAGL--GIGLITVPFLIHNAEVA 158
            .::...:....:...:..:|.:::..|:.    :...:.:|.:.|:  ||...|:|..:  .|:|
  Rat   110 MVNKWGRKRTLLINNVFAITSAVLMGASKAARAFELIIFSRVMVGICAGIAYSTLPMYL--GELA 172

  Fly   159 SNNLRGVNGGMEQCGLALGIFFQVIFT--------TEWTSLIDSNPNEIHGIIGIVVSLFGLAMT 215
            ..||||..|.|.:..:..|:....||:        |.|..|:        .:.| |.:|..|...
  Rat   173 PQNLRGTLGTMTEVFVIFGVLLAQIFSLQTILGNATGWPILL--------ALTG-VPALIQLLSL 228

  Fly   216 ALVVESPIFFLRRNMENRAQQSQEKLLRHNPGGVSAALKEARRYVAESDNRTLGEELVASVMPFL 280
            ....|||.:.|....:....:...:.||.:...|.|.::|.|     ::.||   |.....:..|
  Rat   229 PFFPESPRYTLIEKGDEETTRQALRRLRGHSYNVEAEMEEMR-----TEERT---EKAEGRLSVL 285

  Fly   281 KMLLFRCFVAFSFSLPLTMS---------------IISSTAVAEKGLSLWPIYLFGVLRVIGVMV 330
            .:..||.......|:.:.|:               ||.::|..:...|.:.....||:.::..:|
  Rat   286 NLFTFRPLRWQLISIVVLMAGQQLSGINAVNYYADIIYTSAGVDPTQSQYVTLGSGVINLVMTLV 350

  Fly   331 ALIFLDTLGRKAVSLVGLLVMAGLMLGLAGLYANVTNLISFNLMTSAC---NIALAFQ------V 386
            :...::.|||:      :|:::|  .|:.|               |||   .:||..|      .
  Rat   351 SAFIIERLGRR------ILLLSG--YGICG---------------SACLVLTVALLLQSTVPELS 392

  Fly   387 FAGLFVCSSSAYMGEAF-PMRVKSFLVGVIVI---------IEQIVH----IVVIACVSSVPNKD 437
            :.|: :|..|..:|.:. |..|.|.:...||:         ::..||    .:|.....|:....
  Rat   393 YLGI-ICVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGAVHWLTNFIVGLTFPSIQVAI 456

  Fly   438 FFFQYFLAVGIIMLVGMIFFTVSMPETKKMTLRKAGHRFQKWYDVQM 484
            ..:.:.:..||.:|.....:.| :||||..|..:....|.|...|::
  Rat   457 GAYSFLIFAGICLLTAAYIYVV-IPETKGKTFVEINCIFAKRNGVEV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6901	NP_650531.1	Sugar_tr	85..469	CDD:278511	89/459 (19%)
CG6901	NP_650531.1	MFS	<272..457	CDD:119392	41/222 (18%)
Slc2a7	XP_038967504.1	MFS_GLUT_Class2	26..490	CDD:340990	100/533 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840