DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip89B and Zip88E

DIOPT Version :9

Sequence 1:	NP_536747.2	Gene:	Zip89B / 41975	FlyBaseID:	FBgn0038412	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_650440.2	Gene:	Zip88E / 41847	FlyBaseID:	FBgn0038312	Length:	366	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	114/382 - (29%)
Similarity:	179/382 - (46%)	Gaps:	88/382 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 KVTAMVVLFCASAICGSIPFLLNRCYRWTENQTNARSAIVVKCLLYFGGGVLLATTFLHLLPEVQ 120
            ||.||:||...|.:.|.:|..::       .:...|..:....||.||.|:||||..:|:||||:
  Fly    28 KVLAMLVLGLGSLLFGLLPAFIS-------ERNRRRFPLTASLLLCFGAGILLATALVHILPEVR 85

  Fly   121 EVVEELQECGIIGELTFPLAELLMCCGFFLMYFIEEAMHTYVHHHQKDEAGAAFERGHSIRNSHL 185
            |            ::....||:.||.|||::|||:|.:|.:.              |.:|:::|
  Fly    86 E------------QMDSKFAEVAMCGGFFIIYFIDEFIHYFF--------------GEAIQHTH- 123

  Fly   186 LKPTEGNATTPTAPPAPLAGTAELGTLSVQNLLQNDLEQQKFATKPQQQANGHGHSHGHGHGHSH 250
                ..:|.||...| |...|.:.|..:|.       |:....:.....::||.|.|.|.|.|:|
  Fly   124 ----AHDAETPATEP-PRRPTNDNGYGAVD-------ERAPLLSAEPNTSHGHSHHHSHDHDHNH 176

  Fly   251 LPVIA--------DDADA-------GDMLASSLR---GLFIVSALSLHELFEGMAIGLESSASSV 297
             |..|        :||:|       .:..|.|:.   |||:  |||||...||:|||:::|::.|
  Fly   177 -PASASGCNDASVEDANARICHTSHTEPCAQSMTGTLGLFV--ALSLHSAIEGLAIGVQNSSTKV 238

  Fly   298 WFMFGAVSAHKLVLAFCVGVEL-IVARTRMLLAVLYVLTFAVVSPLGIGIGILINHGEETSGPSL 361
            .|:.|||:.||.|:.||:|:|. ...:|......:.:..||:.:.:|||:|:||     ...|:.
  Fly   239 LFLLGAVACHKFVMGFCLGLEFRSNPQTSFRAQFVGISVFALGAVIGIGLGMLI-----VDVPAA 298

  Fly   362 VSA----ILQGFACGTLIYVVFFEILSKNR-----------SGLRAYLALFVGFLVM 403
            .|:    |:|..|.|||.||...|::.:.:           :|...:..:..||..|
  Fly   299 WSSKTLPIVQALAGGTLFYVTVCEVIPREKARWHSNSTRRWAGFAQFATVLAGFATM 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip89B	NP_536747.2	Zip	53..406	CDD:280666	114/382 (30%)
Zip88E	NP_650440.2	Zip	26..359	CDD:280666	114/382 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I5998
eggNOG	1	0.900	-	-		E1_KOG1558
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I1910
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D471714at33208
OrthoFinder	1	1.000	-	-		FOG0000574
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11040
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970