Protein Alignment Mat89Ba and NOL6

DIOPT Version :9

• Sequence 1: NP_650530.2
• Gene: Mat89Ba / 41973
• FlyBaseID: FBgn0261286
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_075068.2
• Gene: NOL6 / 65083
• HGNCID: 19910
• Length: 1146
• Species: Homo sapiens
• Alignment Length: 1175
• Identity: 397/1175 - (33%)
• Similarity: 588/1175 - (50%)
• Gaps: 118/1175 - (10%)

  Fly    19 GAARTGTQAIAHAGDHSDLDEP-------KPKIAKS------DPPSTAIPKKNNFKQREGTKNVK 70
            |.|..|.|.....|: .::.||       :.|.|.|      :||:..:.:.....:.|   ..|
Human     2 GPAPAGEQLRGATGE-PEVMEPALEGTGKEGKKASSRKRTLAEPPAKGLLQPVKLSRAE---LYK 62

  Fly    71 PPTLEEMKELRDTQNLFHSNLFKLQVKEMLEELQLKQKYTDFIENWLESF------------TAF 123
            .||.||:..||:|:.||||:|.:|||:|:|:|::|.:|..|.|:.:|...            |..
Human    63 EPTNEELNRLRETEILFHSSLLRLQVEELLKEVRLSEKKKDRIDAFLREVNQRVVRVPSVPETEL 127

  Fly   124 TRQ--LKDGLMERTHLEVPMKLSEKPTGFVFSKPTREPYLIGAAATGTLLGPKIVVDVALEMPKE 186
            |.|  |..|:....| :||..:.    |.....|..:..::|:...||.:.|.|.|||||.||:|
Human   128 TDQAWLPAGVRVPLH-QVPYAVK----GCFRFLPPAQVTVVGSYLLGTCIRPDINVDVALTMPRE 187

  Fly   187 SLHKEDYLNLRYDQKRALYLTYVTERMMESPDYAEDQFNFNYYANN-PLKPVLELIPVTKQVNKH 250
            .|..:|.||.||.:||||||.::...:.:.|.:....|:   |.|. .|||.|.|.|..|. .:.
Human   188 ILQDKDGLNQRYFRKRALYLAHLAHHLAQDPLFGSVCFS---YTNGCHLKPSLLLRPRGKD-ERL 248

  Fly   251 LQVRLFITAPLSSFKPGRFVPWNNNIRPSFYGDEWDEKD--PLPSTQHYNANVLFDLTLSENQAQ 313
            :.|||....|...|:|.|.:|..||:|.::|..:....|  |.|.|..||..||.|..|..:...
Human   249 VTVRLHPCPPPDFFRPCRLLPTKNNVRSAWYRGQSPAGDGSPEPPTPRYNTWVLQDTVLESHLQL 313

  Fly   314 LDKAFKSRRNFQDGLLLLKVWLRQRQLDIGYSGFGAHILAAFIVYLNTQRILHQSSSSYQVARTV 378
            |.....|.:..:||:.|||||||||:||.|..||...:::..:|:|.:.|.:|.:.|.|||.|:|
Human   314 LSTILSSAQGLKDGVALLKVWLRQRELDKGQGGFTGFLVSMLVVFLVSTRKIHTTMSGYQVLRSV 378

  Fly   379 WNQLANTDWT-KGISLSVAPIQT-EELNKFAEHYDVCFIDFTGQHNLCANIPLYLYQRVREEAKL 441
            ...||.||.| .||||.::...: ..|..|.:.:.|.|:|.:|..||||::....|.:|:.||:|
Human   379 LQFLATTDLTVNGISLCLSSDPSLPALADFHQAFSVVFLDSSGHLNLCADVTASTYHQVQHEARL 443

  Fly   442 AVELLNDMKLNSFPLIFMQKCPLYSRVDNILKISNYSCINQML-TLHSHPRIKYDFANYGYPQLL 505
            ::.||:....:.|.|:.|...|:....|::|.:...|.:.... .|...|.::.:..:| ....|
Human   444 SMMLLDSRADDGFHLLLMTPKPMIRAFDHVLHLRPLSRLQAACHRLKLWPELQDNGGDY-VSAAL 507

  Fly   506 HLLTELLKKGLAERVHSILPLETATAAWPVEKKAPVIGKY-----IQLGLILQPEHAYQVLNKGP 565
            ..||.||::||..|::.:.........|.:.:..|   |:     :.|||:|:||....||..||
Human   508 GPLTTLLEQGLGARLNLLAHSRPPVPEWDISQDPP---KHKDSGTLTLGLLLRPEGLTSVLELGP 569

  Fly   566 AANDDHEGAEEFRRFWGEKSNLRRFQDGSITEAVVWGTAQDSPAKKRLIVRQIVLHLLEHHLQLD 630
            .|  |...|.:||:|||.:|.|||||||:|.|||||..|  |.::||||..|:|.|||..|..:.
Human   570 EA--DQPEAAKFRQFWGSRSELRRFQDGAIREAVVWEAA--SMSQKRLIPHQVVTHLLALHADIP 630

  Fly   631 SKEVQYIGGELDQVYQLSPWFKVNKLKTKLPLGQDTDAEALSPHVIRCYDELARQLHGLNDLPLE 695
            ...|.|:||.||.:.|        .||.....|::....|     :||||:|:|.|.||..|||.
Human   631 ETCVHYVGGPLDALIQ--------GLKETSSTGEEALVAA-----VRCYDDLSRLLWGLEGLPLT 682

  Fly   696 IVSISGVSPIFRYCE---PQPVLPQALLVENRILASSI--------------QRVVIQLGQSGKW 743
            :.::.|..|:.||.|   |.||.|.....|.....||:              ..||..|..||:|
Human   683 VSAVQGAHPVLRYTEVFPPTPVRPAFSFYETLRERSSLLPRLDKPCPAYVEPMTVVCHLEGSGQW 747

  Fly   744 PTELGALRALKTAFLIEIGEKLEAQCRLHWVMSADGLLVLKQGYCFLIELAHNKELALLKQEVTE 808
            |.:..|::.::.||.:.:.|.|..|..|....:|....|||.|:.|.|.:|:.:|..:||:..:.
Human   748 PQDAEAVQRVRAAFQLRLAELLTQQHGLQCRATATHTDVLKDGFVFRIRVAYQREPQILKEVQSP 812

  Fly   809 RGITTYIDNAASRSLERQHYILPKVSGALHSLHQTYSAFGSTVLLAKRWLATQLLDDGLWPDMAT 873
            .|:.:..|.|||..|||....||.::.|||.|.|.:.||.....|||||:..|||.:| :.|.:.
Human   813 EGMISLRDTAASLRLERDTRQLPLLTSALHGLQQQHPAFSGVARLAKRWVRAQLLGEG-FADESL 876

  Fly   874 ELLVAHLF--QQRYAPQSIAAPQTGFIRFLQLLSHSDFNGELFLLNFNNSWQEQQIADLEHNYRS 936
            :|:.|.||  .:.:.|.|  :||.||:|||.|:|..|:......:|.||....::..::...:.:
Human   877 DLVAAALFLHPEPFTPPS--SPQVGFLRFLFLVSTFDWKNNPLFVNLNNELTVEEQVEIRSGFLA 939

  Fly   937 NRQSYPPLAVATSYDMQHAGRLWTSDQSPSQRVLGHVTRLARHALEIIETSLMSK----DLRFVR 997
            .|...|.:.:.|..|.:::  :||.| .||.::|..:..||..||.::|..||..    |:|.|
Human   940 ARAQLPVMVIVTPQDRKNS--VWTQD-GPSAQILQQLVVLAAEALPMLEKQLMDPRGPGDIRTV- 1000

  Fly   998 PAQLFRASNEGYDLVIQFKPDLVPNSLSYDLGSPFVSF-----SQPNFS--LPRAGSDYIARIVG 1055
                ||...:.||::|:..|..:|.. ...:.||..||     |||..|  :|..|.|.....:.
Human  1001 ----FRPPLDIYDVLIRLSPRHIPRH-RQAVDSPAASFCRGLLSQPGPSSLMPVLGYDPPQLYLT 1060

  Fly  1056 LLRSAYSDFAAFFYNPHGGKELGIVWRPPTEFAAKPFKV--TELQACSPCGNKKVQVLK-ETLLE 1117
            .||.|:.|.|.|||:.|||:.:|::|: ||.|..:|||.  |:.:.....|.:.|.|.. |.:||
Human  1061 QLREAFGDLALFFYDQHGGEVIGVLWK-PTSFQPQPFKASSTKGRMVMSRGGELVMVPNVEAILE 1124

  Fly  1118 DFKLL 1122
            ||.:|
Human  1125 DFAVL 1129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mat89Ba	NP_650530.2	Nrap	166..1130	CDD:281764	349/1001 (35%)
NOL6	NP_075068.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		12/46 (26%)
		Nrap	165..1138	CDD:281764	349/1003 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147601
Domainoid	1	1.000	100	1.000	Domainoid score	I7044
eggNOG	1	0.900	-	-		E1_KOG2054
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41505
Inparanoid	1	1.050	516	1.000	Inparanoid score	I1303
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54062
OrthoDB	1	1.010	-	-		D148067at33208
OrthoFinder	1	1.000	-	-		FOG0003992
OrthoInspector	1	1.000	-	-		oto88664
orthoMCL	1	0.900	-	-		OOG6_102389
Panther	1	1.100	-	-	LDO	PTHR17972
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1619
SonicParanoid	1	1.000	-	-		X2755
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	16	15.840