Protein Alignment Mat89Ba and nol-6

DIOPT Version :9

• Sequence 1: NP_650530.2
• Gene: Mat89Ba / 41973
• FlyBaseID: FBgn0261286
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: NP_001364780.1
• Gene: nol-6 / 173520
• WormBaseID: WBGene00021789
• Length: 1035
• Species: Caenorhabditis elegans
• Alignment Length: 1183
• Identity: 272/1183 - (22%)
• Similarity: 484/1183 - (40%)
• Gaps: 290/1183 - (24%)

  Fly    89 SNLFKL--------QVKEMLE-ELQLKQKYTDFIENWLESFTAFTRQLKDGLMERTHLEVPMKLS 144
            ||.|||        ..|:::| :.|:.||    |:|.||:       .|:|          .|:.
 Worm    11 SNAFKLLCEDTAPKSNKKLIEKQRQIAQK----IKNVLET-------SKNG----------PKIQ 54

  Fly   145 EKPTGFVFSKPTREP--YLIGAA-ATGTLL------GPKIVV------DVALEMPKESLHKEDYL 194
            .|...|......:.|  :|..|. ||.:.:      .||.:|      .:.:|:|.::|...|:|
 Worm    55 YKNLDFWTEFDVKHPLHHLQKAVDATSSSIPEFQWTPPKSIVITEKGQQIFIEIPPKALGNRDFL 119

  Fly   195 NLRYDQKRALYLTYVTERM---------------MESPDYAE---DQFNFNYYANNPLKPVLELI 241
            ||.|..||..:..:|...:               .:.|.:|:   |.....:|.     |.|.
 Worm   120 NLTYAAKRGHFACHVARLLSGKFEKVEFTAGGAHRDDPIFADILVDGVRIGFYC-----PELA-- 177

  Fly   242 PVTKQVNKHLQVRLFITAPLSSFKPGRFVPWNNNIRP-SFYGDEWDEKDPLPSTQHYNANVLFDL 305
                                   |..||.|...|:|| :.:.|.:.|.:  .:|..:|..:|:.:
 Worm   178 -----------------------KTKRFAPNIGNLRPATIFEDLFKETE--IATPKFNQRMLWSI 217

  Fly   306 TLSENQAQLDKAFKSRRNFQDGLLLLKVWLRQRQLDIGYSGFGAHILAAFIVYLNTQRILHQSSS 370
            ...|...:::|..|:::..:..:.||..:...|.|....:..   ||.|.:|.|.....:.::..
 Worm   218 LELEIAQEMEKELKAQKTARLAIFLLGNFFENRHLQHAITPI---ILTARVVRLVKNGKITENQE 279

  Fly   371 SYQVARTVWNQLANTDWTKGISLSVAPIQTE-ELNKFAEHYDVCFIDFTGQHNLCANIPLYLYQR 434
            ...|.|.::.....  |:......|..::.: ::.::::.:||..:  ....||.:|:.....:|
 Worm   280 ILTVLRVIFEDFIT--WSADDVEFVDSVEDDVDVEEYSQLFDVNLV--WKNLNLASNLTKNYMER 340

  Fly   435 VREEAKLAVELLNDMKLNSFPLIFMQKCPLYSRVDNILK-------------------ISNYSCI 480
            :::|..:...||.  ::.:|..||::|.|:::..|::.:                   |.|...|
 Worm   341 MKKELTICYPLLG--QVYAFDPIFIEKLPVFAHYDHVARLHINISQLAEHLVEFGIDSIDNRDVI 403

  Fly   481 NQMLTLHSHPRI------KYDFANYGYPQLLHLLTELLKK---GLAE-----RVHSILPLETATA 531
            ::.:....| :|      :|||..      :|.::...:|   .|:|     |..:.|....:|:
 Worm   404 HKFVLSFEH-KIEQTMSERYDFVG------IHDISSNAEKSTWSLSEYPEKYRQKTYLIGFRSTS 461

  Fly   532 AWPVEKKAPVIGKYIQLGLILQPEHAYQVLNKGPAA--NDDHEGAEEFRRFWGEKSNLRRFQDGS 594
            .|    |.|                    |..||.|  ||    |:|||..|.|.|.||:|.|..
 Worm   462 GW----KNP--------------------LTVGPPAQTND----AKEFRELWKETSELRKFADTR 498

  Fly   595 ITEAVVWGTAQDSPAKKRLIVRQIVLHLLEHHLQLDSKEVQYIGGELDQVYQL-SPWFKVNKLKT 658
            |.|.|||   .:.|::|   |.:.||              |::   |.:::.| :..|....|.:
 Worm   499 ICECVVW---SEKPSEK---VPRAVL--------------QFV---LQKMFSLPATCFSWRALTS 540

  Fly   659 KLPLGQDTDAEALSPH-------VIRCYDELARQLHGLNDLPLEIVSISGVSPIFRYCEP----- 711
                 ..|.|||...|       |.:.|.:|:..|.||..|||.|.::.|:|...|..||
 Worm   541 -----SSTSAEADQQHEKKSQEAVFKAYTDLSTVLRGLKGLPLMITNVHGISGYLRGSEPAYPSV 600

  Fly   712 --------------QPVLPQALLVENRILASSIQRVVIQLGQSGKWPTELGALRALKTAFLIEIG 762
                          ..|||:   :....|.:....|.|:|..||||..::.|:|.|.::|.::|.
 Worm   601 FAATSSTNKSSEDQHYVLPE---IGKIPLFTPTVTVHIKLEYSGKWGNDVEAIRRLTSSFYVKIA 662

  Fly   763 EKLEAQCRLHWVMSADGLLVLKQGYCFLIELAHNKELALLKQEVTERGITTYIDNAASR------ 821
            |:|..|.:|..|.:.|.|.:||.|..|.|.:.:::.|.:|:::|.:     ..|:.|||
 Worm   663 ERLREQHKLTAVPTIDQLFILKSGIVFKIVVVNDRILTILEEDVQK-----LKDSGASRIESSIQ 722

  Fly   822 ----SLERQHYIL-PKVSGALHSLHQTYSAFGSTVLLAKRWLATQLLDDGLWPDMATELLVAHLF 881
                |:.::.:|. |.:..:|.|...::..|||||.|.|:||.::.|......|...||||....
 Worm   723 GMRLSMWKKKFISEPLLQLSLQSFSTSHKFFGSTVQLFKKWLGSKFLSGHHLNDHIIELLVVAAI 787

  Fly   882 QQR--YAPQSIAAPQTGFIRFLQLLSHSDFNGELFLLNF-NNSWQEQQIADLEHNYRSNRQSYPP 943
            .::  ..|||   ..:.|.|.|.|:|...::....:::| ...:.|.:.:.||..:...|...||
 Worm   788 GKKGQVPPQS---TWSSFCRLLSLISTHPWSARPLIVDFGTKGFSEDERSKLEEKFIKMRPILPP 849

  Fly   944 LAVATSYDMQHAGRLWTSDQSPSQRVLGHVTRLARHALEI------------IETSLMSKDLRFV 996
            :.|.  |:..|.|..:|. ::|...||..:..:||.||::            :||||::::|
 Worm   850 MVVI--YEEDHLGSKFTR-ENPQGIVLNRLVAVAREALKMMEKQAFGEKSIEMETSLLTENL--- 908

  Fly   997 RPAQLFRASNEGYDLVIQFKPDLVPNSLSYDLGSPFVSFSQPNFSLPRAGSDYIARIVGLLRSAY 1061
                      ..||.:|..:|..|....:.....|....|:....:|....|.:..:|..|.:::
 Worm   909 ----------SPYDAIINLEPCAVVRKKALMERKPPAETSKFRQKIPVVELDPVDELVYQLNNSF 963

  Fly  1062 SDFAAFFYNPHGGKELGIVWRPPTEFAAKPFKVTELQACSPCGNKKVQVLKETLLEDFKLLLKDF 1126
            ...|.||||.:||..:|::::|..:  ..|.|::.........:..:::.::.:||:.::|.:.
 Worm   964 QQVAMFFYNKYGGHHIGVMFKPQED--EVPAKISRCSLHKSVSDSTLRLNRDEILENIQILGQG- 1025

  Fly  1127 YLRIATPEELKRE 1139
               |.:..:||::
 Worm  1026 ---IVSDVQLKKQ 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mat89Ba	NP_650530.2	Nrap	166..1130	CDD:281764	247/1083 (23%)
nol-6	NP_001364780.1	Nrap	104..231	CDD:397747	31/158 (20%)
		Nrap_D2	237..365	CDD:407477	25/136 (18%)
		Nrap_D3	369..528	CDD:407478	48/216 (22%)
		Nrap_D4	542..748	CDD:407479	60/213 (28%)
		Nrap_D5	750..899	CDD:407480	42/154 (27%)
		Nrap_D6	908..1030	CDD:407481	27/140 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159592
Domainoid	1	1.000	68	1.000	Domainoid score	I6414
eggNOG	1	0.900	-	-		E1_KOG2054
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I2499
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54062
OrthoDB	1	1.010	-	-		D148067at33208
OrthoFinder	1	1.000	-	-		FOG0003992
OrthoInspector	1	1.000	-	-		oto18161
orthoMCL	1	0.900	-	-		OOG6_102389
Panther	1	1.100	-	-	LDO	PTHR17972
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1619
SonicParanoid	1	1.000	-	-		X2755
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840