Protein Alignment CG6126 and SV2B

DIOPT Version :9

• Sequence 1: NP_650528.1
• Gene: CG6126 / 41967
• FlyBaseID: FBgn0038407
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001309960.1
• Gene: SV2B / 9899
• HGNCID: 16874
• Length: 683
• Species: Homo sapiens
• Alignment Length: 677
• Identity: 139/677 - (20%)
• Similarity: 217/677 - (32%)
• Gaps: 270/677 - (39%)

  Fly     8 EDLMGKLGEFGKYQFLQFFLQVLSGLTAGMHMLSLVTVAAVPEHRCFIEGVDNSSLSVTPWNSSA 72
            |.:|.:.|. |::|::.||            :|.|..:|         :||:            .
Human    96 ETIMDECGH-GRFQWILFF------------VLGLALMA---------DGVE------------V 126

  Fly    73 ILAAIPLKPNGELESCLMFDPSSPGTNTTINCERYVYDTTYYKTSRTIDWNFVCDRRWMGAIVQT 137
            .:.:..| |:.|.:.||  ..|..|                                .:|.||
Human   127 FVVSFAL-PSAEKDMCL--SSSKKG--------------------------------MLGMIV-- 154

  Fly   138 VFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAY 202
              .||:..||..|||||||:|||.|...|...........:|:..|.:|:..|.:.|| |..||.
Human   155 --YLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGI-GIGGAL 216

  Fly   203 ICGFVLTMELVGPTKRTVCG--ITFQAVF--AGGIMLVAGWGALIPDRQWLQVIYGLH-GCLFLG 262
            ...|....|.:...||   |  :::..:|  .||:...|...::||...|     |.. |..:..
Human   217 PIVFAYFSEFLSREKR---GEHLSWLGIFWMTGGLYASAMAWSIIPHYGW-----GFSMGTNYHF 273

  Fly   263 HWW-------------------WLDESPRWLWMQGRAAEAVDIVAK--GLRINGSGIPVDKEYYV 306
            |.|                   ::.||||:|...|:..||..|:.:  ...:...|.| :|.:.|
Human   274 HSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTP-EKVFTV 337

  Fly   307 QKAKQQAAAEE----KSSAG---------LSDLFRT-----------PNLRMKTLNVCLCWFANS 347
            ...|.....:|    :||.|         ...:|:.           | .||.||.:.:.|||.:
Human   338 SNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGP-YRMNTLILAVVWFAMA 401

  Fly   348 LVYYGLSL----------------------------------------SAGKLYGNP-------- 364
            ..||||::                                        ..|||..:.
Human   402 FSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKH 466

  Fly   365 ----------------------------------------------------------------- 364
                                                                             
Human   467 VLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLE 531

  Fly   365 -------YLILFIMGLVEFPSYITIVFVLDRLGRRSITSTLMLGGGLCCIVAAYIAQGSTTSTAV 422
                   ||:.|:..|...|..|....::||:||..:....||...:||.   ::..|:  |.:.
Human   532 QDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCF---FLFFGN--SESA 591

  Fly   423 VMAGKLLIAGSFAVIYN----YSAELFPTVVRNSAMG-LGSMCARLSGALTPLITLLDSF--DPK 480
            ::..:.|..|:....:|    .:.||:||..|.:|.| |..:|.  .||:.. .|:..||  ..|
Human   592 MIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCK--FGAILG-NTIFASFVGITK 653

  Fly   481 IPAVLFGVVALISGFWV-MFLPETMNQ 506
            :..:|....:|:.|..: :.||||..|
Human   654 VVPILLAAASLVGGGLIALRLPETREQ 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6126	NP_650528.1	2A0119	15..510	CDD:273328	137/670 (20%)
		MFS	130..501	CDD:119392	115/548 (21%)
SV2B	NP_001309960.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		Sugar_tr	8..683	CDD:331684	139/677 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940